CAS 52299-14-6|Suc-Ala-Ala-Ala-pNA
| Common Name | Suc-Ala-Ala-Ala-pNA | ||
|---|---|---|---|
| CAS Number | 52299-14-6 | Molecular Weight | 451.43 |
| Density | 1.37 g/cm3 | Boiling Point | 923.5ºC at 760 mmHg |
| Molecular Formula | C19H25N5O8 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 512.3ºC |
Names
| Name | N-Succinyl-Ala-Ala-Ala-p-nitroanilide |
|---|---|
| Synonym | More Synonyms |
Suc-Ala-Ala-Ala-pNA BiologicalActivity
| Description | Suc-AAA-pNA?is the substrate of analysis of the reversible inhibition of porcine pancreatic elastase (PPE)[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| Target | IC50: Substrate[1] |
| References | [1]. Panagiota-Yiolanda Stergiou, et al. Kinetic and computational analysis of the reversible inhibition of porcine pancreatic elastase: a structural and mechanistic approach. J Enzyme Inhib Med Chem. 2016;31(sup3):131-139. |
Chemical & Physical Properties
| Density | 1.37 g/cm3 |
|---|---|
| Boiling Point | 923.5ºC at 760 mmHg |
| Molecular Formula | C19H25N5O8 |
| Molecular Weight | 451.43 |
| Flash Point | 512.3ºC |
| Exact Mass | 451.17000 |
| PSA | 199.52000 |
| LogP | 1.68110 |
| Index of Refraction | 1.584 |
| InChIKey | GVUGADOWXGKRAE-SRVKXCTJSA-N |
| SMILES | CC(NC(=O)CCC(=O)O)C(=O)NC(C)C(=O)NC(C)C(=O)Nc1ccc([N+](=O)[O-])cc1 |
| Storage condition | 2-8°C |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | 24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 29242990 |
Articles36
More Articles| A new Kunitz-type plasmin inhibitor from scorpion venom. Toxicon 106 , 7-13, (2015) Kunitz-type peptides from venomous animals are an important source of lead drug candidates towards human plasmin, a target of protease-associated diseases. However, no Kunitz-type plasmin inhibitor fr... | |
| SjAPI, the first functionally characterized Ascaris-type protease inhibitor from animal venoms. PLoS ONE 8(3) , e57529, (2013) Serine protease inhibitors act as modulators of serine proteases, playing important roles in protecting animal toxin peptides from degradation. However, all known serine protease inhibitors discovered... | |
| Purification, kinetical and molecular characterizations of a serine collagenolytic protease from greenshore crag (Carcinus maenas) digestive gland. Comp. Biochem. Physiol. B Biochem. Mol. Biol. 115(1) , 87-95, (1996) A serine collagenolytic protease was purified from a water soluble fraction of greenshore crab digestive gland by acidic precipitation, gel filtration on a Sephadex G-50 column, ion-exchange chromatog... |
Synonyms
| 4-[[(2S)-1-[[(2S)-1-[[(2S)-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid |
| EINECS 257-823-5 |
| N-Succinyl-L-alanyl-L-alanyl-L-alanine 4-nitroanilide N-Succinyl-tri-L-alanine 4-nitroanilide |
| MFCD00036774 |
