CAS 7423-96-3|3-fluoro-L-tyrosine

Introduction:Basic information about CAS 7423-96-3|3-fluoro-L-tyrosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name3-fluoro-L-tyrosine
CAS Number7423-96-3Molecular Weight199.18
Density/Boiling Point/
Molecular FormulaC9H10FNO3Melting Point260-261°C
MSDS/Flash Point>110°C

Names

Name3-Fluoro-L-tyrosine
SynonymMore Synonyms

3-fluoro-L-tyrosine BiologicalActivity

Description3-Fluoro-L-tyrosine is a tyrosine analogue, inhibits transamination by tyrosine aminotransferase (TAT). And 3-FluoroL-tyrosine has been shown to be biologically incorporated into proteins in place of tyrosine. 3-Fluoro-L-tyrosine pretends to be the substrate of rat liver tyrosine aminotransferase, markedly disturbs the Tyr-TAT association[1][2].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease
References

[1]. Iron A, et al. Action of the phosphonic analogue of tyrosine and of other tyrosine derivatives on rat liver tyrosine aminotransferase. Amino Acids. 1993 Feb;5(1):33-7.  

[2]. Phillips RS, et al. Effects of tyrosine ring fluorination on rates and equilibria of formation of intermediates in the reactions of carbon-carbon lyases. Eur J Biochem. 1997 Mar 1;244(2):658-63.  

Chemical & Physical Properties

Melting Point260-261°C
Molecular FormulaC9H10FNO3
Molecular Weight199.18
Flash Point>110°C
Exact Mass199.06400
PSA83.55000
LogP1.18600
Index of Refraction-9 ° (C=1, 1mol/L HCl)
InChIKeyVIIAUOZUUGXERI-ZETCQYMHSA-N
SMILESNC(Cc1ccc(O)c(F)c1)C(=O)O
StabilityStable. Incompatible with strong oxidizing agents, strong reducing agents.

Safety Information

Hazard CodesT
Risk PhrasesR25
Safety PhrasesS22-S24/25
RIDADR2811
WGK Germany3
Packaging GroupII
Hazard Class6.1
HS Code2922509090

Customs

HS Code2922509090
Summary2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

(2S)-2-amino-3-(3-fluoro-4-hydroxyphenyl)propanoic acid
MFCD00002607
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