Introduction:Basic information about CAS 7423-96-3|3-fluoro-L-tyrosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 3-fluoro-L-tyrosine |
|---|
| CAS Number | 7423-96-3 | Molecular Weight | 199.18 |
|---|
| Density | / | Boiling Point | / |
|---|
| Molecular Formula | C9H10FNO3 | Melting Point | 260-261°C |
|---|
| MSDS | / | Flash Point | >110°C |
|---|
Names
| Name | 3-Fluoro-L-tyrosine |
|---|
| Synonym | More Synonyms |
|---|
3-fluoro-L-tyrosine BiologicalActivity
| Description | 3-Fluoro-L-tyrosine is a tyrosine analogue, inhibits transamination by tyrosine aminotransferase (TAT). And 3-FluoroL-tyrosine has been shown to be biologically incorporated into proteins in place of tyrosine. 3-Fluoro-L-tyrosine pretends to be the substrate of rat liver tyrosine aminotransferase, markedly disturbs the Tyr-TAT association[1][2]. |
|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
|---|
| References | [1]. Iron A, et al. Action of the phosphonic analogue of tyrosine and of other tyrosine derivatives on rat liver tyrosine aminotransferase. Amino Acids. 1993 Feb;5(1):33-7. [2]. Phillips RS, et al. Effects of tyrosine ring fluorination on rates and equilibria of formation of intermediates in the reactions of carbon-carbon lyases. Eur J Biochem. 1997 Mar 1;244(2):658-63. |
|---|
Chemical & Physical Properties
| Melting Point | 260-261°C |
|---|
| Molecular Formula | C9H10FNO3 |
|---|
| Molecular Weight | 199.18 |
|---|
| Flash Point | >110°C |
|---|
| Exact Mass | 199.06400 |
|---|
| PSA | 83.55000 |
|---|
| LogP | 1.18600 |
|---|
| Index of Refraction | -9 ° (C=1, 1mol/L HCl) |
|---|
| InChIKey | VIIAUOZUUGXERI-ZETCQYMHSA-N |
|---|
| SMILES | NC(Cc1ccc(O)c(F)c1)C(=O)O |
|---|
| Stability | Stable. Incompatible with strong oxidizing agents, strong reducing agents. |
|---|
Safety Information
| Hazard Codes | T |
|---|
| Risk Phrases | R25 |
|---|
| Safety Phrases | S22-S24/25 |
|---|
| RIDADR | 2811 |
|---|
| WGK Germany | 3 |
|---|
| Packaging Group | II |
|---|
| Hazard Class | 6.1 |
|---|
| HS Code | 2922509090 |
|---|
Customs
| HS Code | 2922509090 |
|---|
| Summary | 2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
|---|
Synonyms
| (2S)-2-amino-3-(3-fluoro-4-hydroxyphenyl)propanoic acid |
| MFCD00002607 |