CAS 2124-57-4|Vitamin K2(35)
Introduction：Basic information about CAS 2124-57-4|Vitamin K2(35), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Vitamin K2(35) | ||
|---|---|---|---|
| CAS Number | 2124-57-4 | Molecular Weight | 648.999 |
| Density | 0.961 | Boiling Point | 720.1±60.0 °C at 760 mmHg |
| Molecular Formula | C46H64O2 | Melting Point | 54ºC |
| MSDS | / | Flash Point | 254.9±29.9 °C |
Names
| Name | menaquinone-7 |
|---|---|
| Synonym | More Synonyms |
Vitamin K2(35) BiologicalActivity
| Description | Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors[1]. Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins [2]. Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS)[3]. |
|---|---|
| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Others >>Others |
| References | [1]. Thijssen, H H., et al., 1994. Vitamin K distribution in rat tissues: dietary phylloquinone is a source of tissue menaquinone-4. The British journal of nutrition. 72(3): 415-25. [2]. Conly, J M., et al., 1994. The contribution of vitamin K2 (menaquinones) produced by the intestinal microflora to human nutritional requirements for vitamin K. The American journal of gastroenterology. 89(6): 915-23. [3]. Peeters FECM, et al. Bicuspid Aortic Valve Stenosis and the Effect of Vitamin K2 on Calcification Using 18F-Sodium Fluoride Positron Emission Tomography/Magnetic Resonance: The BASIK2 Rationale and Trial Design. Nutrients. 2018 Mar 21;10(4). pii: E386. |
Chemical & Physical Properties
| Density | 0.961 |
|---|---|
| Boiling Point | 720.1±60.0 °C at 760 mmHg |
| Melting Point | 54ºC |
| Molecular Formula | C46H64O2 |
| Molecular Weight | 648.999 |
| Flash Point | 254.9±29.9 °C |
| Exact Mass | 648.490601 |
| PSA | 34.14000 |
| LogP | 17.05 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.532 |
| InChIKey | RAKQPZMEYJZGPI-LJWNYQGCSA-N |
| SMILES | CC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCCC(C)=CCC1=C(C)C(=O)c2ccccc2C1=O |
| Storage condition | -20C |
Safety Information
| RIDADR | NONH for all modes of transport |
|---|
Synonyms
| Vitamin K2(35) |
| Menaquinone 7 |
| 2-((2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18,22,26-heptaen-1-yl)-3-methylnaphthalene-1,4-dione |
| 2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18,22,26-heptaen-1-yl]-3-methylnaphthalene-1,4-dione |
| Vitamin K2 MK-7 |
| 2-(3,7,11,15,19,23,27-Heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthoquinone |
| 1,4-Naphthalenedione,2-(3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-,(all-E) |
| 1,4-Naphthalenedione, 2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyl-2,6,10,14,18,22,26-octacosaheptaen-1-yl]-3-methyl- |
| (all-E)-2-(3,7,11,15,19,23,27-Heptamethyl-2,6,10,14,18,22,26-octacosaheptaenyl)-3-methyl-1,4-naphthalenedione |
| MK-7 |
| 2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-Heptamethyloctacosa-2,6,10,14,18,22,26-heptaen-1-yl]-3-methyl-1,4-naphthoquinone |
| 2-methyl-3-all-trans-farnesyl digeranyl-1,4-naphthoquinone |
| MK 7 |
| Menaquinone-7 |
| 2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-heptamethyloctacosa-2,6,10,14,18,22,26-heptaenyl]-3-methylnaphthalene-1,4-dione |
| Vitamin MK 7 |
| 2-[(2E,6E,10E,14E,18E,22E)-3,7,11,15,19,23,27-Heptamethyl-2,6,10,14,18,22,26-octacosaheptaen-1-yl]-3-methyl-1,4-naphthoquinone |
| Menaquinone K7 |
