CAS 64967-39-1|FA-Phe-Gly-Gly-OH
| Common Name | FA-Phe-Gly-Gly-OH | ||
|---|---|---|---|
| CAS Number | 64967-39-1 | Molecular Weight | 399.397 |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 842.3±65.0 °C at 760 mmHg |
| Molecular Formula | C20H21N3O6 | Melting Point | 245ºC (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | 463.2±34.3 °C |
Names
| Name | N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly |
|---|---|
| Synonym | More Synonyms |
FA-Phe-Gly-Gly-OH BiologicalActivity
| Description | N-[3-(2-Furyl)acryloyl]-Phe-Gly-Gly (FAPGG) is a synthetic cromogenic substrate for angiotensin converting enzyme (ACE) determination[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Metabolic Enzyme/Protease >>Angiotensin-converting Enzyme (ACE) |
| References | [1]. Hsu FL, et al. Both dioscorin, the tuber storage protein of yam (Dioscorea alata cv. Tainong No. 1), and its peptic hydrolysates exhibited angiotensin converting enzyme inhibitory activities. J Agric Food Chem. 2002 Oct 9;50(21):6109-13. |
Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 842.3±65.0 °C at 760 mmHg |
| Melting Point | 245ºC (dec.)(lit.) |
| Molecular Formula | C20H21N3O6 |
| Molecular Weight | 399.397 |
| Flash Point | 463.2±34.3 °C |
| Exact Mass | 399.143036 |
| PSA | 137.74000 |
| LogP | 1.77 |
| Vapour Pressure | 0.0±3.3 mmHg at 25°C |
| Index of Refraction | 1.603 |
| InChIKey | ZDLZKMDMBBMJLI-FDMDGMSGSA-N |
| SMILES | O=C(O)CNC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)C=Cc1ccco1 |
| Storage condition | −20°C |
| Water Solubility | NH4OH 1 M: 50 mg/mL, clear to slightly turbid, yellow |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | 22-24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | OH2915000 |
| HS Code | 29321900 |
Articles33
More Articles| Effect of power ultrasound pretreatment on peptidic profiles and angiotensin converting enzyme inhibition of milk protein concentrate hydrolysates. J. Sci. Food Agric. 94(12) , 2420-8, (2014) The use of power ultrasound as a pretreatment to enhance the hydrolysis of milk protein concentrate (MPC) and subsequent angiotensin converting enzyme (ACE) inhibitory activity has been studied. Liqui... | |
| Assessment and optimization of kinetic methods for angiotensin-converting enzyme in plasma. Clin. Chem. 39(2) , 312-6, (1993) In the kinetic angiotensin-converting enzyme (ACE) method, a practical and optimal buffer is 80 mmol/L borate buffer at pH 8.2 (37 degrees C). A lag phase is detected in the reaction, and a 5-min incu... | |
| Evidence for the negative cooperativity of the two active sites within bovine somatic angiotensin-converting enzyme. FEBS Lett. 550(1-3) , 84-8, (2003) The somatic isoform of angiotensin-converting enzyme (ACE) consists of two homologous domains (N- and C-domains), each bearing a catalytic site. We have used the two-domain ACE form and its individual... |
Synonyms
| Glycine, N-[(2E)-3-(2-furanyl)-1-oxo-2-propen-1-yl]-L-phenylalanylglycyl- |
| N-[(2E)-3-(2-Furyl)prop-2-enoyl]-L-phenylalanylglycylglycine |
| N-[3-(2-Furyl)acryloyl]-L-phenylalanyl-glycyl-glycine |
| N-[(2E)-3-(2-Furyl)-2-propenoyl]-L-phenylalanylglycylglycine |
| FAPGG |
