CAS 1761-71-3|Bis(4-aminocyclohexyl)methane

Introduction：Basic information about CAS 1761-71-3|Bis(4-aminocyclohexyl)methane, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Preparation
6. Customs
7. Articles2
8. Synonyms

Common Name	Bis(4-aminocyclohexyl)methane
CAS Number	1761-71-3	Molecular Weight	210.359
Density	0.9±0.1 g/cm3	Boiling Point	320.0±0.0 °C at 760 mmHg
Molecular Formula	C₁₃H₂₆N₂	Melting Point	60-65°C
MSDS	ChineseUSA	Flash Point	144.8±17.9 °C
Symbol	GHS05, GHS07, GHS08, GHS09	Signal Word	Danger

Names

Name	4,4'-Diaminodicyclohexyl methane
Synonym	More Synonyms

Chemical & Physical Properties

Density	0.9±0.1 g/cm3
Boiling Point	320.0±0.0 °C at 760 mmHg
Melting Point	60-65°C
Molecular Formula	C₁₃H₂₆N₂
Molecular Weight	210.359
Flash Point	144.8±17.9 °C
Exact Mass	210.209595
PSA	52.04000
LogP	2.49
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.499
Water Solubility	Insoluble (

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GX1530000

CHEMICAL NAME :: Cyclohexylamine, 4,4'-methylenebis-

CAS REGISTRY NUMBER :: 1761-71-3

LAST UPDATED :: 199710

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C13-H26-N2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 670 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0571204

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,481,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 20175 mg/kg/1.5Y-I

TOXIC EFFECTS :: Gastrointestinal - changes in structure or function of salivary glands Liver - fatty liver degeneration Kidney, Ureter, Bladder - interstitial nephritis

REFERENCE :: JJATDK JAT, Journal of Applied Toxicology. (John Wiley & Sons Ltd., Baffins Lane, Chichester, W. Sussex PO19 1UD, UK) V.1- 1981- Volume(issue)/page/year: 11,367,1991

Safety Information

Symbol	GHS05, GHS07, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H302-H314-H317-H373-H411
Precautionary Statements	P273-P280-P305 + P351 + P338-P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T+:Verytoxic;N:Dangerous for the environment;
Risk Phrases	R26;R34;R51/53
Safety Phrases	S26-S28-S36/37/39-S45-S61
RIDADR	UN 2928 6.1/PG 2
WGK Germany	2
RTECS	GX1530000
Packaging Group	III
Hazard Class	8
HS Code	2921300090

Preparation

Customs

HS Code	2921300090
Summary	2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles2

Allergic contact dermatitis from dicyclohexylmethane-4,4'-diisocyanate.

Contact Dermatitis 48(6) , 305-9, (2003)

From August 1999 to April 2001, there was an outbreak of severe eczema at a factory manufacturing medical equipment. A glue, mainly based on the isocyanate dicyclohexylmethane-4,4'-diisocyanate (DMDI)...

Toxicity of 1,4-bis(aminocyclohexyl)methane.

J. Appl. Toxicol. 11(5) , 367-71, (1991)

1,4-Bis(aminocyclohexyl)methane (PACM; CAS No. 1761-71-3) is a white solid considered for use in polymeric systems. PACM is moderately toxic systemically, with the acute oral lethal dose in rats betwe...

Synonyms

4,4-Methylenebiscyclohexylamine

hlr4448

4,4'-methanediyldicyclohexanamine

bis(para-amino-cyclohexyl)methane

Cyclohexanamine, 4,4'-methylenebis-

EINECS 217-168-8

Bis(4-aminocyclohexyl)methane

Wondamine HM

p-aminodicyclohexylmethane

DICYKAN

HLR 4219

4,4'-Methylenebis(aminocyclohexane)

4,4'-Methylenedicyclohexanamine

TRANS,TRANS-4,4'-METHYLENEBIS(CYCLOHEXYLAMINE)

4,4'-Methylenebis(cyclohexylaMine)

4,4'-Diaminodicyclohexylmethane

4,4'-methylene bis(cyclohexylamine)

4-((4-aminocyclohexyl)methyl)cyclohexanamine

Bis-(p-aminocyclohexyl)methane

MFCD00001496

di(4-aminocyclohexyl)-methane

4,4-Methylenebis(Cyclohexylamine)

bis-(4-amino cyclohexyl)-methane

PACM20

wandaminhm

Amicure PACM

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