CAS 2784-73-8|6-acetylmorphine

Introduction：Basic information about CAS 2784-73-8|6-acetylmorphine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Articles26
6. Synonyms

Common Name	6-acetylmorphine
CAS Number	2784-73-8	Molecular Weight	327.37400
Density	1.38g/cm3	Boiling Point	470.2ºC at 760mmHg
Molecular Formula	C₁₉H₂₁NO₄	Melting Point	184-189ºC
MSDS	/	Flash Point	238.2ºC
Symbol	GHS02, GHS06	Signal Word	Danger

Names

Name	6-Acetyl Morphine
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.38g/cm3
Boiling Point	470.2ºC at 760mmHg
Melting Point	184-189ºC
Molecular Formula	C₁₉H₂₁NO₄
Molecular Weight	327.37400
Flash Point	238.2ºC
Exact Mass	327.14700
PSA	59.00000
LogP	1.70680
Vapour Pressure	1.83E-09mmHg at 25°C
Index of Refraction	1.665
InChIKey	JJGYGPZNTOPXGV-SSTWWWIQSA-N
SMILES	CC(=O)OC1C=CC2C3Cc4ccc(O)c5c4C2(CCN3C)C1O5

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QC7814500

CHEMICAL NAME :: Morphinan-3,6-alpha-diol, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-, 6-acetate

CAS REGISTRY NUMBER :: 2784-73-8

LAST UPDATED :: 199512

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C19-H21-N-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 59 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year: 85,317,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intracerebral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 147 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJPHAZ European Journal of Pharmacology. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1967- Volume(issue)/page/year: 85,317,1982

Safety Information

Symbol	GHS02, GHS06
Signal Word	Danger
Hazard Statements	H225-H302 + H312-H319-H331
Precautionary Statements	P210-P261-P280-P305 + P351 + P338-P311
Hazard Codes	F: Flammable;Xn: Harmful;
Risk Phrases	11-20/21/22-36
Safety Phrases	16-36/37-26
RIDADR	UN 1648 3/PG 2

Articles26

Dynamic vaccine blocks relapse to compulsive intake of heroin.

Proc. Natl. Acad. Sci. U. S. A. 110(22) , 9036-41, (2013)

Heroin addiction, a chronic relapsing disorder characterized by excessive drug taking and seeking, requires constant psychotherapeutic and pharmacotherapeutic interventions to minimize the potential f...

Validation of a gas chromatography-ion trap-tandem mass spectrometry assay for the simultaneous quantification of cocaine, benzoylecgonine, cocaethylene, morphine, codeine, and 6-acetylmorphine in aqueous solution, blood, and skeletal muscle tissue.

J. Anal. Toxicol. 36(1) , 1-11, (2012)

A gas chromatography-ion trap-tandem mass spectrometry method was developed and validated for the simultaneous solid-phase extraction and quantification of cocaine, benzoylecgonine, cocaethylene, morp...

Simultaneous determination of xylazine, free morphine, codeine, 6-acetylmorphine, cocaine and benzoylecgonine in postmortem blood by UPLC-MS-MS.

J. Anal. Toxicol. 36(5) , 319-26, (2012)

Xylazine, a veterinary sedative, has been found as an adulterant of heroin in street drugs in Puerto Rico. It was found in combination with free morphine and 6-acetylmorphine, codeine, cocaine and ben...

Synonyms

[(4R,4aR,7S,7aR,12bS)-9-hydroxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl] acetate

Recommended......