CAS 5987-76-8|6-Chloro-2-iodo-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)puri

Introduction：Basic information about CAS 5987-76-8|6-Chloro-2-iodo-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)puri, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	6-Chloro-2-iodo-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine
CAS Number	5987-76-8	Molecular Weight	538.68
Density	1.98g/cm3	Boiling Point	643.3ºC at 760 mmHg
Molecular Formula	C₁₆H₁₆ClIN₄O₇	Melting Point	181-183ºC
MSDS	/	Flash Point	342.9ºC

Names

Name	6-Chloro-2-iodo-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine
Synonym	More Synonyms

BiologicalActivity

Description	6-Chloro-2-iodo-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

Density	1.98g/cm3
Boiling Point	643.3ºC at 760 mmHg
Melting Point	181-183ºC
Molecular Formula	C₁₆H₁₆ClIN₄O₇
Molecular Weight	538.68
Flash Point	342.9ºC
Exact Mass	537.97500
PSA	131.73000
LogP	1.40820
Index of Refraction	1.713
InChIKey	BYOJIJDSBSWKKE-SDBHATRESA-N
SMILES	CC(=O)OCC1OC(n2cnc3c(Cl)nc(I)nc32)C(OC(C)=O)C1OC(C)=O

Synonyms

acetic acid (2r,3r,4r,5r)-3,4-diacetoxy-5-(6-chloro-2-iodo-purin-9-yl)-tetrahydro-furan-2-ylmethyl ester

MFCD03701153

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