Introduction:Basic information about CAS 81202-00-8|L-Glutamic acid-5-13C, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | L-Glutamic acid-5-13C |
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| CAS Number | 81202-00-8 | Molecular Weight | 148.12200 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C413CH9NO4 | Melting Point | 205ºC (dec.)(lit.) |
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| MSDS | ChineseUSA | Flash Point | / |
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Names
| Name | (2S)-2-aminopentanedioic acid |
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| Synonym | More Synonyms |
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L-Glutamic acid-5-13C BiologicalActivity
| Description | L-Glutamic acid-5-13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals. |
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| Related Catalog | Signaling Pathways >>Neuronal Signaling >>iGluRSignaling Pathways >>Apoptosis >>ApoptosisSignaling Pathways >>Apoptosis >>FerroptosisResearch Areas >>Neurological DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>iGluR |
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| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
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| References | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |
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Chemical & Physical Properties
| Melting Point | 205ºC (dec.)(lit.) |
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| Molecular Formula | C413CH9NO4 |
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| Molecular Weight | 148.12200 |
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| Exact Mass | 148.05700 |
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| PSA | 100.62000 |
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| InChIKey | WHUUTDBJXJRKMK-MYXYCAHRSA-N |
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| SMILES | NC(CCC(=O)O)C(=O)O |
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Safety Information
| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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Synonyms
| I04-8437 |
| [5-13C]glutamic acid |
| L-Glutamic acid-5-13C |
| MFCD00144591 |
| (5-13C)-L-Glutamic acid |