CAS 81202-00-8|L-Glutamic acid-5-13C

Introduction:Basic information about CAS 81202-00-8|L-Glutamic acid-5-13C, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameL-Glutamic acid-5-13C
CAS Number81202-00-8Molecular Weight148.12200
Density/Boiling Point/
Molecular FormulaC413CH9NO4Melting Point205ºC (dec.)(lit.)
MSDSChineseUSAFlash Point/

Names

Name(2S)-2-aminopentanedioic acid
SynonymMore Synonyms

L-Glutamic acid-5-13C BiologicalActivity

DescriptionL-Glutamic acid-5-13C is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
Related CatalogSignaling Pathways >>Neuronal Signaling >>iGluRSignaling Pathways >>Apoptosis >>ApoptosisSignaling Pathways >>Apoptosis >>FerroptosisResearch Areas >>Neurological DiseaseSignaling Pathways >>Membrane Transporter/Ion Channel >>iGluR
In VitroStable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

Melting Point205ºC (dec.)(lit.)
Molecular FormulaC413CH9NO4
Molecular Weight148.12200
Exact Mass148.05700
PSA100.62000
InChIKeyWHUUTDBJXJRKMK-MYXYCAHRSA-N
SMILESNC(CCC(=O)O)C(=O)O

Safety Information

RIDADRNONH for all modes of transport
WGK Germany3

Synonyms

I04-8437
[5-13C]glutamic acid
L-Glutamic acid-5-13C
MFCD00144591
(5-13C)-L-Glutamic acid
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