CAS 624-84-0|formohydrazide

Introduction:Basic information about CAS 624-84-0|formohydrazide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Nameformohydrazide
CAS Number624-84-0Molecular Weight60.055
Density1.1±0.1 g/cm3Boiling Point129.7±23.0 °C at 760 mmHg
Molecular FormulaCH4N2OMelting Point52-57 °C(lit.)
MSDSUSAFlash Point32.2±22.6 °C
Symbol
GHS07
Signal WordWarning

Names

NameFormylhydrazine
SynonymMore Synonyms

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point129.7±23.0 °C at 760 mmHg
Melting Point52-57 °C(lit.)
Molecular FormulaCH4N2O
Molecular Weight60.055
Flash Point32.2±22.6 °C
Exact Mass60.032364
PSA55.12000
LogP-2.05
Vapour Pressure10.0±0.2 mmHg at 25°C
Index of Refraction1.424
InChIKeyXZBIXDPGRMLSTC-UHFFFAOYSA-N
SMILESNNC=O
Storage condition2-8°C
Water SolubilitySoluble

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LQ8615000
CHEMICAL NAME :
Formic acid, hydrazide
CAS REGISTRY NUMBER :
624-84-0
BEILSTEIN REFERENCE NO. :
0635759
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C-H4-N2-O
MOLECULAR WEIGHT :
60.07
WISWESSER LINE NOTATION :
ZMVH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
120 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 18,645,1968
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
65 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 4,259,1961 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
73 gm/kg/43W-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
REFERENCE :
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 37,960,1978 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4064 No. of Facilities: 17 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 919 (estimated) No. of Female Employees: 306 (estimated)

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH315-H319-H335
Precautionary StatementsP305 + P351 + P338
Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXn:Harmful;
Risk PhrasesR20/21/22;R36/37/38
Safety PhrasesS26-S36-S36/37/39
RIDADRNONH for all modes of transport
WGK Germany3
RTECSLQ8615000
HS Code2928000090

Customs

HS Code2928000090
Summary2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles3

More Articles
N-ethyl-N-formylhydrazine tumorigenesis in mice.

Carcinogenesis 1(1) , 61-5, (1980)

N-ethyl-N-formylhydrazine (EFH) was administered as a 0.02% solution in drinking water continuously for life to randomly bred Swiss mice, from 6 weeks of age. The treatment induced tumors of the lungs...

Traceless liquid-phase synthesis of 3-alkylamino-4, 5-disubstituted-1, 2, 4-triazoles on polyethylene glycol (PEG). Zong Y-X, et al.

Tetrahedron Lett. 46(31) , 5139-41, (2005)

Synthesis of NB-506, a new anticancer agent. Ohkubo M, et al.

Tetrahedron 53(2) , 585-92, (1997)

Synonyms

MFCD00007589
Formic hydrazide
formohydrazide
formic acid hydrazide
Hydrazine, formyl-
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