Introduction：Basic information about CAS 28705-46-6|Ethyl 7-(Diethylamino)coumarin-3-carboxylate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ethyl 7-(Diethylamino)coumarin-3-carboxylate |
|---|
| CAS Number | 28705-46-6 | Molecular Weight | 289.32600 |
|---|
| Density | 1.204g/cm3 | Boiling Point | 455.6ºC at 760mmHg |
|---|
| Molecular Formula | C16H19NO4 | Melting Point | 86ºC |
|---|
| MSDS | / | Flash Point | 229.3ºC |
|---|
Names
| Name | ethyl 7-(diethylamino)-2-oxochromene-3-carboxylate |
|---|
| Synonym | More Synonyms |
|---|
BiologicalActivity
| Description | Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate is a potent and selective inhibitor of hMAO-B with an IC50 of 45.52 μM[1]. |
|---|
| Related Catalog | Signaling Pathways >>Neuronal Signaling >>Monoamine OxidaseResearch Areas >>Neurological Disease |
|---|
| References | [1]. Secci D, et al. Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives. Eur J Med Chem. 2011 Oct;46(10):4846-52. |
|---|
Chemical & Physical Properties
| Density | 1.204g/cm3 |
|---|
| Boiling Point | 455.6ºC at 760mmHg |
|---|
| Melting Point | 86ºC |
|---|
| Molecular Formula | C16H19NO4 |
|---|
| Molecular Weight | 289.32600 |
|---|
| Flash Point | 229.3ºC |
|---|
| Exact Mass | 289.13100 |
|---|
| PSA | 59.75000 |
|---|
| LogP | 2.81590 |
|---|
| Vapour Pressure | 1.73E-08mmHg at 25°C |
|---|
| Index of Refraction | 1.57 |
|---|
| InChIKey | MSOLGAJLRIINNF-UHFFFAOYSA-N |
|---|
| SMILES | CCOC(=O)c1cc2ccc(N(CC)CC)cc2oc1=O |
|---|
Safety Information
Customs
| HS Code | 2932209090 |
|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|---|
Synonyms
| 7-diethylamino-2-oxo-2H-1-benzopyran-3-carboxylic acid ethyl ester |
| 7-(Diethylamino)coumarin-3-carboxylic Acid Ethyl Ester |
| ethyl 7-diethylaminocoumarin-3-carboxylate |
| Ethyl 7-(Diethylamino)coumarin-3-carboxylate |
| 7-diethylamino-2-oxo-2H-chromene-3-carboxylic acid ethyl ester |
| 7-diethylaminocoumarin-3-carboxylic acid ethyl ester |
| ethyl 7-(diethylamino)-2-oxo-2H-[1]benzopyran-3-carboxylate |
| ethyl 7-diethylamino-2-oxo-2H-chromene-3-carboxylate |
