CAS 41024-91-3|Pentaethylene glycol di(p-toluenesulfonate)

Introduction：Basic information about CAS 41024-91-3|Pentaethylene glycol di(p-toluenesulfonate), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Articles4
7. Synonyms

Common Name	Pentaethylene glycol di(p-toluenesulfonate)
CAS Number	41024-91-3	Molecular Weight	546.65100
Density	1.26	Boiling Point	661.4ºC at 760mmHg
Molecular Formula	C₂₄H₃₄O₁₀S₂	Melting Point	/
MSDS	ChineseUSA	Flash Point	353.8ºC
Symbol	GHS07	Signal Word	Warning

Names

Name	penta(ethylene glycol) di-p-toluenesulfonate
Synonym	More Synonyms

BiologicalActivity

Description	Pentaethylene glycol di(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

Chemical & Physical Properties

Density	1.26
Boiling Point	661.4ºC at 760mmHg
Molecular Formula	C₂₄H₃₄O₁₀S₂
Molecular Weight	546.65100
Flash Point	353.8ºC
Exact Mass	546.15900
PSA	140.42000
LogP	4.64220
Index of Refraction	n20/D 1.524(lit.)
InChIKey	BUHGDYPBQWWWQS-UHFFFAOYSA-N
SMILES	Cc1ccc(S(=O)(=O)OCCOCCOCCOCCOCCOS(=O)(=O)c2ccc(C)cc2)cc1
Water Solubility	Not miscible or difficult to mix in water.

Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	36/37/38
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2909499000

Customs

HS Code	2909499000
Summary	2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles4

Pure Appl. Chem. 65 , 585, (1993)

Tetrahedron 49 , 6019, (1993)

Chem Express 8 , 471, (1993)

Synonyms

Pentaethylene glycol di-p-toluenesulfonate

2-[2-[2-[2-[2-(4-methylphenyl)sulfonyloxyethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate

MFCD00012204

Recommended......