CAS 306-83-2|1,1-Dichloro-2,2,2-trifluoroethane

Introduction：Basic information about CAS 306-83-2|1,1-Dichloro-2,2,2-trifluoroethane, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
MUTATION DATA
4. Safety Information
5. Customs
6. Synonyms

Common Name	1,1-Dichloro-2,2,2-trifluoroethane
CAS Number	306-83-2	Molecular Weight	152.93100
Density	1,475 g/cm3	Boiling Point	27.6°C
Molecular Formula	C₂HCl₂F₃	Melting Point	-107°C
MSDS	/	Flash Point	48.2 °F
Symbol	GHS02, GHS06, GHS08	Signal Word	Danger

Names

Name	1,1-Dichloro-2,2,2-trifluoroethane
Synonym	More Synonyms

Chemical & Physical Properties

Density	1,475 g/cm3
Boiling Point	27.6°C
Melting Point	-107°C
Molecular Formula	C₂HCl₂F₃
Molecular Weight	152.93100
Exact Mass	151.94100
LogP	2.35240
Index of Refraction	1.3392 (10ºC)
Storage condition	2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KI1108000

CHEMICAL NAME :: Ethane, 2,2-dichloro-1,1,1-trifluoro-

CAS REGISTRY NUMBER :: 306-83-2

BEILSTEIN REFERENCE NO. :: 1736763

LAST UPDATED :: 199807

DATA ITEMS CITED :: 19

MOLECULAR FORMULA :: C2-H-Cl2-F3

MOLECULAR WEIGHT :: 152.93

WISWESSER LINE NOTATION :: GYGXFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 9 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory stimulation

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 32000 ppm/4H

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 74000 ppm/1H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 300 ppm/6H/13W-I

TOXIC EFFECTS :: Liver - other changes Endocrine - hypoglycemia Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1000 ppm/6H/90D-I

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in adrenal weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10000 ppm/6H/4W-I

TOXIC EFFECTS :: Behavioral - general anesthetic Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 10000 ppm/6H/13W-I

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Liver - hepatitis (hepatocellular necrosis), diffuse Blood - changes in erythrocyte (RBC) count

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5000 ppm/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 300 ppm/6H

SEX/DURATION :: male 4 week(s) pre-mating female 4 week(s) pre-mating - 7 week(s) post-birth

TOXIC EFFECTS :: Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 500 ppm/6H

SEX/DURATION :: female 6-18 day(s) after conception

TOXIC EFFECTS :: Reproductive - Maternal Effects - other effects

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 30 pph/3H

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0530498-1

Safety Information

Symbol	GHS02, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H225-H301 + H311 + H331-H370-H420
Precautionary Statements	P210-P260-P280-P301 + P310-P311
Hazard Codes	T:Toxic;
Risk Phrases	R23/24/25;R39
Safety Phrases	S36/37-S45
RIDADR	3163
HS Code	2903399090
Flash Point(F)	48.2 °F
Flash Point(C)	9 °C

Customs

HS Code	2903399090
Summary	2903399090. brominated,fluorinated or iodinated derivatives of acyclic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Synonyms

2,2-DIALLYL-AZETIDINE

2,2-dichloro-3,3,3-trifluoroethane

MFCD00042132

CF3CHCl2

Fron123

F123

hfa123

1,1,1-trifluoro-2,2-dichloroethane

2,2-dichloro-1,1,1-trifluoroethane

EINECS 206-190-3

r123

FC-123

cfc-123

HFC123

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