CAS 75-37-6|Difluoroethane

CHEMICAL IDENTIFICATION

RTECS NUMBER :

KI1410000

CHEMICAL NAME :

Ethane, 1,1-difluoro-

CAS REGISTRY NUMBER :

75-37-6

BEILSTEIN REFERENCE NO. :

1696900

LAST UPDATED :

199710

DATA ITEMS CITED :

15

MOLECULAR FORMULA :

C2-H4-F2

MOLECULAR WEIGHT :

66.06

WISWESSER LINE NOTATION :

FYF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

>1500 mg/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity)

TYPE OF TEST :

LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

64000 ppm/4H

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

977 gm/m3/2H

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :

TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :

Inhalation

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2000 ppm/6H/2Y-I

TOXIC EFFECTS :

Kidney, Ureter, Bladder - other changes in urine composition Nutritional and Gross Metabolic - changes in metals, not otherwise specified

MUTATION DATA

TEST SYSTEM :

Insect - Drosophila melanogaster

DOSE/DURATION :

98 pph/10M

REFERENCE :

ENVRAL Environmental Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1967- Volume(issue)/page/year: 7,275,1974 *** REVIEWS *** TOXICOLOGY REVIEW FAZMAE Fortschritte der Arzneimittelforschung. Progress in Drug Research. (Birkhauser Boston, Inc., c/o Springer-Verlag New York, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1959- Volume(issue)/page/year: 18,365,1974 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-HUNGARY:TWA 200 mg/m3;STEL 500 mg/m3 JAN 1993 OEL-RUSSIA:STEL 3000 mg/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82202 No. of Facilities: 36 (estimated) No. of Industries: 4 No. of Occupations: 6 No. of Employees: 516 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82202 No. of Facilities: 1550 (estimated) No. of Industries: 7 No. of Occupations: 27 No. of Employees: 132833 (estimated) No. of Female Employees: 116164 (estimated)