CAS 2312-35-8|2-(4-(tert-Butyl)phenoxy)cyclohexyl prop-2-yn-1-yl sulfite
| Common Name | 2-(4-(tert-Butyl)phenoxy)cyclohexyl prop-2-yn-1-yl sulfite | ||
|---|---|---|---|
| CAS Number | 2312-35-8 | Molecular Weight | 350.472 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 450.7±45.0 °C at 760 mmHg |
| Molecular Formula | C19H26O4S | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 226.4±28.7 °C |
| Symbol | GHS05, GHS06, GHS08, GHS09 | Signal Word | Danger |
Names
| Name | propargite |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | Propargite is a pesticide used to kill mites. Propargite induces β-cell necrosis preceded by DNA damage. Propargite induces MIN6 cell death with an IC50 of 1 μM[1]. |
|---|---|
| Related Catalog | Research Areas >>Infection |
| References | [1]. Ting Zhou, et al. A hPSC-based Platform to Discover Gene-Environment Interactions That Impact Human β-cell and Dopamine Neuron Survival. Nat Commun. 2018 Nov 16;9(1):4815. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 450.7±45.0 °C at 760 mmHg |
| Molecular Formula | C19H26O4S |
| Molecular Weight | 350.472 |
| Flash Point | 226.4±28.7 °C |
| Exact Mass | 350.155182 |
| PSA | 63.97000 |
| LogP | 4.81 |
| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
| Index of Refraction | 1.561 |
| InChIKey | ZYHMJXZULPZUED-UHFFFAOYSA-N |
| SMILES | C#CCOS(=O)OC1CCCCC1Oc1ccc(C(C)(C)C)cc1 |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1480 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 14,515,1969
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >940 mg/m3/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,719,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71. Discontinued. Volume(issue)/page/year: 9,119,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 780 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TGANAK Tsitologiya i Genetika. Cytology and Genetics. For English translation, see CYGEDX. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 16(1),45,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 10300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A589,1985 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989
Safety Information
| Symbol | GHS05, GHS06, GHS08, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H315-H318-H331-H351-H410 |
| Precautionary Statements | P261-P273-P280-P305 + P351 + P338-P311-P501 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | T:Toxic |
| Risk Phrases | R23;R38;R40;R41;R50/53 |
| Safety Phrases | S26-S36/37/39-S45-S60-S61 |
| RIDADR | UN 2810 |
| RTECS | WT2900000 |
| Packaging Group | III |
| Hazard Class | 9 |
| HS Code | 2920909014 |
Customs
| HS Code | 2920909014 |
|---|---|
| Summary | 2920909014 2-(4-(tert-butyl)phenoxy)cyclohexyl prop-2-yn-1-yl sulfite。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0% |
Articles24
More Articles| Permeation of Comite through protective gloves. J. Hazard. Mater. 137(1) , 165-71, (2006) The goal of the study was to assess how protective disposable (Safeskin) and chemical protective (Sol-Vex) nitrile gloves were against Comite emulsifiable concentrate formulation containing propargite... | |
| Genotoxic effects of the pesticides Rubigan, Omite and Rovral in root-meristem cells of Crepis capillaris L. Mutat. Res. 652(2) , 191-7, (2008) Three pesticides have been studied for their genotoxicity by the use of assays in the plant Crepis capillaris, aimed at measuring chromosomal aberrations, micronuclei and sister chromosome exchange (S... | |
| Toxicity of three acaricides to Tetranychus urticae (Tetranychidae: Acari) and Orius insidiosus (Anthocoridae: Hemiptera). J. Econ. Entomol. 99(1) , 54-9, (2006) Management for twospotted spider mite, Tetranychus urticae Koch, populations in peanut, Arachis hypogaea L., relies on acaricides. The outcomes of acaricide applications are most predictable when comp... |
Synonyms
| Propargite |
| d014 |
| do14 |
| Propargiet |
| Sulfurous acid, 2-[4-(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propynyl ester |
| (1RS,2RS |
| comite |
| Sulfurous Acid 2-[4-(1,1-Dimethylethyl)phenoxy]cyclohexyl 2-Propynyl Ester |
| EINECS 219-006-1 |
| 2-[4-(2-Methyl-2-propanyl)phenoxy]cyclohexyl 2-propyn-1-yl sulfite |
| Omit |
| BPPS |
| MFCD00072448 |
| Omite |
| progi |
| 1RS,2SR)-2-(4-tert-butylphenoxy)cyclohexyl prop-2-ynyl sulfite |
| 2-(4-tert-Butylphenoxy)cyclohexyl 2-propynyl sulfite |
| 2-(4-tert-Butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite |
| PROP 57 |
| omait |
| 2-(4-tert-Butylphenoxy)cyclohexyl-prop-2-in-1-ylsulfit |
| Sulfurous Acid 2-(p-tert-Butylphenoxy)cyclohexyl 2-Propynyl Ester |
| (1Ξ,2Ξ)-2-(4-tert-butylphenoxy)cyclohexyl prop-2-yn-1-yl sulfite |
| Propargil |
| 2-[4-(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propyn-1-yl sulfite |
| Sulfurous acid, 2-[4-(1,1-dimethylethyl)phenoxy]cyclohexyl 2-propyn-1-yl ester |
| 2-(4-(tert-Butyl)phenoxy)cyclohexyl prop-2-yn-1-yl sulfite |
| RETADOR |
