CAS 627-30-5|3-Chloro-1-propanol

CHEMICAL IDENTIFICATION

RTECS NUMBER :

UA8930000

CHEMICAL NAME :

1-Propanol, 3-chloro-

CAS REGISTRY NUMBER :

627-30-5

BEILSTEIN REFERENCE NO. :

0773655

LAST UPDATED :

199710

DATA ITEMS CITED :

5

MOLECULAR FORMULA :

C3-H7-Cl-O

MOLECULAR WEIGHT :

94.55

WISWESSER LINE NOTATION :

Q3G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2300 mg/kg

TOXIC EFFECTS :

Behavioral - muscle contraction or spasticity Gastrointestinal - ulceration or bleeding from stomach Liver - other changes

MUTATION DATA

TYPE OF TEST :

Mutation in microorganisms

TEST SYSTEM :

Bacteria - Salmonella typhimurium

DOSE/DURATION :

33 ug/plate

REFERENCE :

ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 9(Suppl 9),1,1987

J. Reprod. Fertil. 111(2) , 285-90, (1997)

When incubated in the absence of exogenous substrates, washed boar spermatozoa maintained a high energy charge potential (ECP) for at least 5 h. Addition of 3-chloro-1-hydroxypropanone, an inhibitor o...

Int. J. Androl. 23(4) , 243-7, (2000)

3-(36)Chloro-1-hydroxypropanone (CHOP), a specific inhibitor of sperm glycolysis in vitro, is rapidly metabolized by the male rat to alpha-chlorohydrin, 3-chlorolactate and the inhibitory sperm metabo...

Reprod. Fertil. Dev. 9(6) , 577-81, (1997)

Boar sperm rapidly interconverted dihydroxyacetone phosphate and glyceraldehyde 3-phosphate, produced fructose-1,6-bisphosphate, approximately equilibrium concentrations of fructose 6-phosphate and gl...