CAS 465-18-9|Polyporenic acid C

Introduction:Basic information about CAS 465-18-9|Polyporenic acid C, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NamePolyporenic acid C
CAS Number465-18-9Molecular Weight482.69500
Density/Boiling Point/
Molecular FormulaC31H46O4Melting Point/
MSDS/Flash Point/

Names

Name(2S)-2-[(10S,13R,14R,16R,17R)-16-hydroxy-4,4,10,13,14-pentamethyl-3-oxo-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-17-yl]-6-methyl-5-methylideneheptanoic acid
SynonymMore Synonyms

Polyporenic acid C BiologicalActivity

DescriptionPolyporenic acid C is a lanostane-type triterpenoid isolated from P. cocos. Polyporenic acid C induces cell apoptosis through the death receptor-mediated apoptotic pathway without the involvement of the mitochondria. Polyporenic acid C is promising agent for lung cancer therapy[1].
Related CatalogSignaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>Cancer
Target

IC50: apoptosis[1]

References

[1]. Ling H, et al. Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells.Mol Carcinog. 2009 Jun;48(6):498-507.

Chemical & Physical Properties

Molecular FormulaC31H46O4
Molecular Weight482.69500
Exact Mass482.34000
PSA74.60000
LogP6.74480
InChIKeyKPKYWYZPIVAHKU-WMNQUVFJSA-N
SMILESC=C(CCC(C(=O)O)C1C(O)CC2(C)C3=CCC4C(C)(C)C(=O)CCC4(C)C3=CCC12C)C(C)C
Storage condition2-8℃

Synonyms

Polyporenic acid C
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