Introduction：Basic information about CAS 6691-83-4|Cinobufaginol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Cinobufaginol |
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| CAS Number | 6691-83-4 | Molecular Weight | 458.54400 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C26H34O7 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | Cinobufaginol |
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| Synonym | More Synonyms |
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Cinobufaginol BiologicalActivity
| Description | Cinobufaginol is a natural bufadienolide isolated from toad venom which has been widely used for centuries in China to treat different diseases, especially for cancer. Cinobufaginol potently inhibits the activity against human nasopharyngeal carcinoma cell lines with IC50s of 803 μΜ and 1.270 μΜ for CNE-1 and CNE-2Z, respectively[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| References | [1]. Liu JS, et al. Anti-tumor effects and 3D-quantitative structure-activity relationship analysis of bufadienolidesfrom toad venom. Fitoterapia. 2019 Apr;134:362-371. |
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Chemical & Physical Properties
| Molecular Formula | C26H34O7 |
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| Molecular Weight | 458.54400 |
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| Exact Mass | 458.23000 |
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| PSA | 109.50000 |
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| LogP | 2.77230 |
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| InChIKey | KDRVIPFIZZDLGB-CDIOGTMDSA-N |
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| SMILES | CC(=O)OC1C(c2ccc(=O)oc2)C2(C)CCC3C(CCC4CC(O)CCC43CO)C23OC13 |
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Safety Information
Synonyms
| 5beta-Bufa-20,22-dienolide,14,15beta-epoxy-3beta,16beta,19-trihydroxy-,16-acetate |
