CAS 29706-84-1|5'-O-Trt-Zidovudine

Introduction：Basic information about CAS 29706-84-1|5'-O-Trt-Zidovudine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 5'-O-Trt-Zidovudine BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	5'-O-Trt-Zidovudine
CAS Number	29706-84-1	Molecular Weight	509.56
Density	/	Boiling Point	/
Molecular Formula	C₂₉H₂₇N₅O₄	Melting Point	103-104 °C(Solv: toluene (108-88-3))
MSDS	/	Flash Point	/

Names

Name	1-[(2R,4S,5S)-4-azido-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Synonym	More Synonyms

5'-O-Trt-Zidovudine BiologicalActivity

Description	3′-Azido-3′-deoxy-5′-O-(triphenylmethyl)thymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

Melting Point	103-104 °C(Solv: toluene (108-88-3))
Molecular Formula	C₂₉H₂₇N₅O₄
Molecular Weight	509.56
Exact Mass	509.20600
PSA	123.33000
LogP	4.68516
InChIKey	AZPSSDWPMSICSH-JIMJEQGWSA-N
SMILES	Cc1cn(C2CC(N=[N+]=[N-])C(COC(c3ccccc3)(c3ccccc3)c3ccccc3)O2)c(=O)[nH]c1=O
Storage condition	2-8℃

Synonyms

3-Azido-3-deoxy-5-O-triphenylmethylthymidine

3'-Azido-3'-deoxy-5'-O-tritylthymidine

Thymidine,3'-azido-3'-deoxy-5'-O-trityl-(8CI)

Thymidine,3'-azido-3'-deoxy-5'-O-(triphenylmethyl)

5'-O-Trt-Zidovudine

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