CAS 1075-06-5|2,2-Dihydroxy-1-phenylethan-1-one

[1]. Tania Kundu, et al. Expeditious and eco-friendly synthesis of new multifunctionalized pyrrole derivatives and evaluation of their antioxidant property. Bioorg Chem. 2020 May;98:103734.

CHEMICAL IDENTIFICATION

RTECS NUMBER :

KM5775180

CHEMICAL NAME :

Ethanone, 2,2-dihydroxy-1-phenyl-

CAS REGISTRY NUMBER :

1075-06-5

BEILSTEIN REFERENCE NO. :

2437741

LAST UPDATED :

199612

DATA ITEMS CITED :

1

MOLECULAR FORMULA :

C8-H8-O3

MOLECULAR WEIGHT :

152.16

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

500 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 1,365,1959

Proc. Soc. Exp. Biol. Med. 148(1) , 177-82, (1975)

Exposure of purified Hageman factor (HF, Factor XII) to phenylglyoxal hydrate (PHG), an agent reacting with arginine residues in protein, inhibited its coagulant properties upon subsequent exposure of...

J. Biol. Chem. 269 , 17809, (1994)

D-Amino-acid oxidase from Rhodotorula gracilis was irreversibly inactivated by phenylglyoxal in a biphasic process. The fast phase was completed in less than 1 min. Its extent was linearly dependent o...

Biochemistry 24(3) , 635-40, (1985)

Mammalian carbonic anhydrase III has previously been shown to catalyze the hydrolysis of p-nitrophenyl phosphate in addition to possessing the conventional CO2 hydratase and p-nitrophenylacetate ester...