Introduction：Basic information about CAS 88122-52-5|Notoginsenoside Fc, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Notoginsenoside Fc |
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| CAS Number | 88122-52-5 | Molecular Weight | 1211.383 |
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| Density | 1.47±0.1 g/cm3 | Boiling Point | / |
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| Molecular Formula | C58H98O26 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | β-D-Glucopyranoside, (3β,12β)-12-hydroxy-20-[(6-O-β-D-xylopyranosyl-β-D-glucopyranosyl)oxy]dammar-24-en-3-yl O-β-D-xylopyranosyl-(1→2)-O-β-D-glucopyranosyl-(1→2) |
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| Synonym | More Synonyms |
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Notoginsenoside Fc BiologicalActivity
| Description | Notoginsenoside Fc, a protopanaxadiol- (PPD-) type saponin isolated from the leaves of Panax notoginseng, effectively counteracts platelet aggregation. Notoginsenoside Fc can accelerate reendothelialization following vascular injury in diabetic rats by promoting autophagy[1]. |
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| Related Catalog | Research Areas >>Cardiovascular DiseaseSignaling Pathways >>Autophagy >>Autophagy |
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| In Vitro | Notoginsenoside Fc (20 μM; for 24 h) markedly upregulates the expression of LC3B and Beclin 1 and downregulated that of p62 in RAOECs[1]. |
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| In Vivo | Notoginsenoside Fc (3.5 mg/kg/day) accelerates reendothelialization and alleviates excessive neointimal formation following carotid artery injury in diabetic Sprague-Dawley rats (200±20 g) in vivo[1]. |
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| References | [1]. Liu J, et al. Notoginsenoside Fc Accelerates Reendothelialization following Vascular Injury in Diabetic Rats by Promoting Endothelial Cell Autophagy. J Diabetes Res. 2019 Sep 3;2019:9696521. |
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Chemical & Physical Properties
| Density | 1.47±0.1 g/cm3 |
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| Molecular Formula | C58H98O26 |
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| Molecular Weight | 1211.383 |
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| Exact Mass | 1210.634644 |
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| PSA | 415.98000 |
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| LogP | 6.60 |
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| Index of Refraction | 1.631 |
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| InChIKey | XBGLCVZQMWKHFC-NMQALWILSA-N |
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| SMILES | CC(C)=CCCC(C)(OC1OC(COC2OCC(O)C(O)C2O)C(O)C(O)C1O)C1CCC2(C)C1C(O)CC1C3(C)CCC(OC4OC(CO)C(O)C(O)C4OC4OC(CO)C(O)C(O)C4OC4OCC(O)C(O)C4O)C(C)(C)C3CCC12C |
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| Water Solubility | Insuluble (1.9E-3 g/L) (25 ºC) |
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Synonyms
| β-D-Glucopyranoside, (3β,12β)-12-hydroxy-20-[(6-O-β-D-xylopyranosyl-β-D-glucopyranosyl)oxy]dammar-24-en-3-yl O-β-D-xylopyranosyl-(1->2)-O-β-D-glucopyranosyl-(1->2)- |
| Dammarane, β-D-glucopyranoside deriv. |
| (3β,12β)-12-Hydroxy-20-{[6-O-(β-D-xylopyranosyl)-β-D-glucopyranosyl]oxy}dammar-24-en-3-yl β-D-xylopyranosyl-(1->;2)-β-D-glucopyranosyl-(1->2)-β-D-glucopyranoside |
| Notoginsenoside Fc |
