CAS 69-89-6|2,6-Dihydroxypurine
Introduction：Basic information about CAS 69-89-6|2,6-Dihydroxypurine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2,6-Dihydroxypurine | ||
|---|---|---|---|
| CAS Number | 69-89-6 | Molecular Weight | 152.111 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 834.9ºC at 760 mmHg |
| Molecular Formula | C5H4N4O2 | Melting Point | 300 °C |
| MSDS | ChineseUSA | Flash Point | 458.7ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 7H-xanthine |
|---|---|
| Synonym | More Synonyms |
2,6-Dihydroxypurine BiologicalActivity
| Description | Xanthine is a purine base found in most human body tissues and fluids and in other organisms. |
|---|---|
| Related Catalog | Research Areas >>Inflammation/ImmunologyNatural Products >>Others |
| Target | Human Endogenous Metabolite |
| In Vitro | A number of stimulants are derived from Xanthine including caffeine and theobromine. Xanthine is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme. |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 834.9ºC at 760 mmHg |
| Melting Point | 300 °C |
| Molecular Formula | C5H4N4O2 |
| Molecular Weight | 152.111 |
| Flash Point | 458.7ºC |
| Exact Mass | 152.033432 |
| PSA | 94.40000 |
| LogP | -0.81 |
| Index of Refraction | 1.636 |
| InChIKey | LRFVTYWOQMYALW-UHFFFAOYSA-N |
| SMILES | O=c1[nH]c(=O)c2[nH]cnc2[nH]1 |
| Storage condition | Store at RT. |
| Water Solubility | NH4OH: freely soluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >3333 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3600 mg/kg/18W-I
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 80 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - tumors
MUTATION DATA - TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 262 umol/L
- REFERENCE :
- MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 3,193,1988 *** REVIEWS *** TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3901 No. of Facilities: 68 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 2546 (estimated) No. of Female Employees: 786 (estimated)
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - mouse Lymphocyte
- DOSE/DURATION :
- 262 umol/L
- REFERENCE :
- MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 3,193,1988 *** REVIEWS *** TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3901 No. of Facilities: 68 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 2546 (estimated) No. of Female Employees: 786 (estimated)
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H317-H319 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36;R43 |
| Safety Phrases | S36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | ZD7700000 |
| HS Code | 2933990090 |
Customs
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| UREOUS ACID |
| Xan |
| xanthicoxide |
| Dioxopurine |
| 9H-xanthine |
| 2,5-DIFLUOROTHIOBENZAMIDE |
| usafcb-17 |
| Xanthine |
| 9H-Purine-2,6(1H,3H)-dione |
| Purine-2,6(1H,3H)-dione |
| Xanthin |
| ISOXANTHINE |
| 2,6-Dihydroxypurine |
| MFCD00078453 |
| 3,7-dihydropurine-2,6-dione |
| Xanthione |
| EINECS 200-718-6 |
| 3,7-dihydro-1H-purine-2,6-dione |
| 1H-Purine-2,6-dione, 3,7-dihydro- |
| 3,7-dihydro-purine-2,6-dione |
| 2,6(1H,3H)-Purinedione |
