CAS 118201-38-0|4,5-Dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazole mononitrate

Introduction：Basic information about CAS 118201-38-0|4,5-Dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazole mononitrate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	4,5-Dihydro-2-(1,2,3,4-tetrahydro-1-naphthalenyl)-1H-imidazole mononitrate
CAS Number	118201-38-0	Molecular Weight	263.29200
Density	1.2 g/cm3	Boiling Point	393.5ºC at 760 mmHg
Molecular Formula	C₁₃H₁₇N₃O₃	Melting Point	/
MSDS	/	Flash Point	191.8ºC

Names

Name	nitric acid,2-(1,2,3,4-tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole
Synonym	More Synonyms

BiologicalActivity

Description	Tetrahydrozoline (Tetryzoline) nitrate , a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion[1][2].
Related Catalog	Research Areas >>Cardiovascular DiseaseSignaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Metabolic Disease
References	[1]. E Kisilevsky, et al. Anterior and posterior segment vasculopathy associated with long-term use of tetrahydrozoline. CMAJ. 2018 Oct 9;190(40):E1208. [2]. Judy Peat, et al.Determination of tetrahydrozoline in urine and blood using gas chromatography-mass spectrometry (GC-MS). Methods Mol Biol. 2010;603:501-8. [3]. Danuta Nowakowska, et al. In vitro effects of vasoconstrictive retraction agents on primary human gingival fibroblasts. Exp Ther Med. 2020 Mar; 19(3): 2037-2044.

Description

Tetrahydrozoline (Tetryzoline) nitrate , a derivative of imidazoline, is an α-adrenergic agonist that causes vasoconstriction. Tetrahydrozoline is widely used for the research of nasal congestion and conjunctival congestion[1][2].

Related Catalog

Research Areas >>Cardiovascular DiseaseSignaling Pathways >>GPCR/G Protein >>Adrenergic ReceptorResearch Areas >>Metabolic Disease

References

[1]. E Kisilevsky, et al. Anterior and posterior segment vasculopathy associated with long-term use of tetrahydrozoline. CMAJ. 2018 Oct 9;190(40):E1208.

[2]. Judy Peat, et al.Determination of tetrahydrozoline in urine and blood using gas chromatography-mass spectrometry (GC-MS). Methods Mol Biol. 2010;603:501-8.

[3]. Danuta Nowakowska, et al. In vitro effects of vasoconstrictive retraction agents on primary human gingival fibroblasts. Exp Ther Med. 2020 Mar; 19(3): 2037-2044.

Chemical & Physical Properties

Density	1.2 g/cm3
Boiling Point	393.5ºC at 760 mmHg
Molecular Formula	C₁₃H₁₇N₃O₃
Molecular Weight	263.29200
Flash Point	191.8ºC
Exact Mass	263.12700
PSA	90.44000
LogP	2.04810
Vapour Pressure	4.8E-06mmHg at 25°C
InChIKey	SVQFLMKSDLCPAY-UHFFFAOYSA-N
SMILES	O=[N+]([O-])O.c1ccc2c(c1)CCCC2C1=NCCN1

Synonyms

I06-1242

Tetrahydrozoline nitrate (JAN)

UNII-8P9X484T3F

Narbel (TN)

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