Introduction：Basic information about CAS 1068-84-4|Aminomalonic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Aminomalonic acid |
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| CAS Number | 1068-84-4 | Molecular Weight | 119.076 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 402.6±40.0 °C at 760 mmHg |
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| Molecular Formula | C3H5NO4 | Melting Point | 240-245°C |
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| MSDS | / | Flash Point | 197.3±27.3 °C |
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Names
| Name | aminomalonic acid |
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| Synonym | More Synonyms |
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Aminomalonic acid BiologicalActivity
| Description | Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (Ki= 0.0023 M) and mouse pancreas (Ki= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis[1][2][3]. |
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| Related Catalog | Research Areas >>Cancer |
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| Target | Ki: 0.0023 M (L-asparagine synthetase from Leukemia 5178Y/AR), 0.0015 M (L-asparagine synthetase from mouse pancreas)[2] |
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| References | [1]. Van Buskirk JJ, et al. Aminomalonic acid: identification in Escherichia coli and atherosclerotic plaque. Proc Natl Acad Sci U S A. 1984 Feb;81(3):722-5. [2]. Milman HA, et al. Aminomalonic acid and its congeners as potential in vivo inhibitors of L-asparagine synthetase. Enzyme. 1979;24(1):36-47. [3]. Kim HY, et al. Discovery of potential biomarkers in human melanoma cells with different metastatic potential by metabolic and lipidomic profiling. Sci Rep. 2017 Aug 18;7(1):8864. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 402.6±40.0 °C at 760 mmHg |
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| Melting Point | 240-245°C |
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| Molecular Formula | C3H5NO4 |
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| Molecular Weight | 119.076 |
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| Flash Point | 197.3±27.3 °C |
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| Exact Mass | 119.021858 |
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| PSA | 100.62000 |
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| LogP | -0.27 |
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| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
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| Index of Refraction | 1.545 |
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| InChIKey | JINBYESILADKFW-UHFFFAOYSA-N |
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| SMILES | NC(C(=O)O)C(=O)O |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2922499990 |
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Customs
| HS Code | 2922499990 |
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| Summary | HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| Aminomalonic acid |
| 2-aminopropanedioic acid |
| aminopropanedioic acid |
| Propanedioic acid, 2-amino- |
| Propanedioic acid, amino- |
