CAS 3785-01-1|2-(4-dimethylaminostyryl)-1-ethylpyridinium iodide
| Common Name | 2-(4-dimethylaminostyryl)-1-ethylpyridinium iodide | ||
|---|---|---|---|
| CAS Number | 3785-01-1 | Molecular Weight | 380.26700 |
| Density | / | Boiling Point | / |
| Molecular Formula | C17H21IN2 | Melting Point | 267ºC (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 2-(4-dimethylaminostyryl)-1-ethylpyridinium iodide |
|---|---|
| Synonym | More Synonyms |
BiologicalActivity
| Description | DASPEI is a fluorescent dye. DASPEI is a styryl dye that stains mitochondria of live cells. DASPEI has a large fluorescence Stokes shift and is taken up relatively slowly as a function of membrane potential[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
| References | [1]. E M Leise. Selective retention of the fluorescent dye DASPEI in a larval gastropod mollusc after paraformaldehyde fixation. Microsc Res Tech. 1996 Apr 15;33(6):496-500. |
Chemical & Physical Properties
| Melting Point | 267ºC (dec.)(lit.) |
|---|---|
| Molecular Formula | C17H21IN2 |
| Molecular Weight | 380.26700 |
| Exact Mass | 380.07500 |
| PSA | 7.12000 |
| LogP | 0.23440 |
| InChIKey | AMAXNNVXIBDEMV-UHFFFAOYSA-M |
| SMILES | CC[n+]1ccccc1C=Cc1ccc(N(C)C)cc1.[I-] |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 17800 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#02331
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36 |
| RIDADR | NONH for all modes of transport |
| RTECS | UU3971000 |
Articles28
More Articles| In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen. Proc. Natl. Acad. Sci. U. S. A. 105 , 9059-64, (2008) The growing resistance to current first-line antimalarial drugs represents a major health challenge. To facilitate the discovery of new antimalarials, we have implemented an efficient and robust high-... | |
| Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science 334 , 1372-7, (2011) Most malaria drug development focuses on parasite stages detected in red blood cells, even though, to achieve eradication, next-generation drugs active against both erythrocytic and exo-erythrocytic f... | |
| The role of efflux systems and the cell envelope in fluorescence changes of the lipophilic cation 2-(4-dimethylaminostyryl)-1-ethylpyridinium in Escherichia coli. Biochim. Biophys. Acta 1278(2) , 205-12, (1996) The interaction of the fluorescent dye 2-(4-dimethylaminostyryl)-1-ethlypyridinium cation (DMP+) with cells of Escherichia coli AN120 (uncA) and AS-1 (acrA) was studied to elucidate the role of the en... |
Synonyms
| GNF-Pf-1399 |
| 2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide |
| GNF-Pf-4643 |
| 4-[2-(1-ethylpyridin-1-ium-2-yl)ethenyl]-N,N-dimethylaniline,iodide |
| GNF-Pf-2708 |
| MFCD00011994 |
| EINECS 223-248-3 |
