Introduction：Basic information about CAS 2920-86-7|Prednisolone hemisuccinate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Prednisolone hemisuccinate |
|---|
| CAS Number | 2920-86-7 | Molecular Weight | 460.51700 |
|---|
| Density | 0,86 g/cm3 | Boiling Point | 358 °C400 mm Hg(lit.) |
|---|
| Molecular Formula | C25H32O8 | Melting Point | 28-32 °C(lit.) |
|---|
| MSDS | / | Flash Point | 265°C/15mm |
|---|
Names
| Name | Prednisolone succinate |
|---|
| Synonym | More Synonyms |
|---|
Prednisolone hemisuccinate BiologicalActivity
| Description | Prednisolone hemisuccinate is a synthetic glucocorticoid, a derivative of cortisol, which is used to treat a variety of inflammatory and auto-immune conditions. |
|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
|---|
Chemical & Physical Properties
| Density | 0,86 g/cm3 |
|---|
| Boiling Point | 358 °C400 mm Hg(lit.) |
|---|
| Melting Point | 28-32 °C(lit.) |
|---|
| Molecular Formula | C25H32O8 |
|---|
| Molecular Weight | 460.51700 |
|---|
| Flash Point | 265°C/15mm |
|---|
| Exact Mass | 460.21000 |
|---|
| PSA | 138.20000 |
|---|
| LogP | 1.97330 |
|---|
| Vapour Pressure | 0mmHg at 25°C |
|---|
| Index of Refraction | 1.6 |
|---|
| InChIKey | APGDTXUMTIZLCJ-CGVGKPPMSA-N |
|---|
| SMILES | CC12C=CC(=O)C=C1CCC1C2C(O)CC2(C)C1CCC2(O)C(=O)COC(=O)CCC(=O)O |
|---|
| Storage condition | 2-8℃ |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- TU4153400
- CHEMICAL NAME :
- Pregna-1,4-diene-3,20-dione, 11-beta,17,21-trihydroxy-, 21-(hydrogen succinate)
- CAS REGISTRY NUMBER :
- 2920-86-7
- LAST UPDATED :
- 199504
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C25-H32-O8
- MOLECULAR WEIGHT :
- 460.57
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- DOSE :
- 50 mg/kg
- SEX/DURATION :
- female 13 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,216,1986
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Parenteral
- DOSE :
- 75 mg/kg
- SEX/DURATION :
- female 13 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - homeostasis
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 36,216,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9553 No. of Facilities: 403 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 4029 (estimated) No. of Female Employees: 2015 (estimated)
|
Safety Information
| Risk Phrases | 61-40 |
|---|
| Safety Phrases | S53-S22-S36/37/39-S45 |
|---|
| RIDADR | NONH for all modes of transport |
|---|
| RTECS | TU4153400 |
|---|
Synonyms
| MFCD00056465 |
| PREDNISOLONE HEMISUCCINATE |
| PREDNISOLONE 21-HEMISUCCINATE |
| prednisolone21-succinate |
| prednisolonbisuccinat |
| EINECS 220-861-8 |
| prednisolut |
| prednisolon hemisuccinate |
| Prednisolone hemisuccinate (usp) |
| prednisolonebisuccinate |
| Prednisolone (hemisuccinate) |
