Introduction:Basic information about CAS 76470-66-1|loracarbef, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | loracarbef |
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| CAS Number | 76470-66-1 | Molecular Weight | 349.76900 |
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| Density | 1.52g/cm3 | Boiling Point | 662.2ºC at 760 mmHg |
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| Molecular Formula | C16H16ClN3O4 | Melting Point | / |
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| MSDS | / | Flash Point | 354.3ºC |
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Names
| Name | loracarbef |
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| Synonym | More Synonyms |
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loracarbef BiologicalActivity
| Description | Loracarbef (Lorabid), a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class[1][2]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
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| In Vitro | Loracarbef (Lorabid) demonstrates excellent activity against isolates of Escherichia coli and Klebsiella, Proteus and Salmonella species[2]. |
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| References | [1]. M Hu, et al. Mechanisms of Transport of Quinapril in Caco-2 Cell Monolayers: Comparison With Cephalexin. Pharm Res. 1995 Aug;12(8):1120-5. [2]. J W Dyke, et al. Antimicrobial Activity of New Antibiotics Against Bacterial Isolates From a Community Hospital. Chemotherapy. Sep-Oct 1993;39(5):315-21. |
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Chemical & Physical Properties
| Density | 1.52g/cm3 |
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| Boiling Point | 662.2ºC at 760 mmHg |
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| Molecular Formula | C16H16ClN3O4 |
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| Molecular Weight | 349.76900 |
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| Flash Point | 354.3ºC |
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| Exact Mass | 349.08300 |
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| PSA | 112.73000 |
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| LogP | 1.73990 |
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| Index of Refraction | 1.677 |
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| InChIKey | JAPHQRWPEGVNBT-UTUOFQBUSA-N |
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| SMILES | NC(C(=O)NC1C(=O)N2C(C(=O)O)=C(Cl)CCC12)c1ccccc1 |
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Synonyms
| (6R,7S)-1,3,10-bisabolatriene |
| 5-(1,5-dimethyl-4-hexenyl)-2-methyl-1,3-cyclohexadiene |
| (-)-(4S,7S)-zingiberene |
| (6R,7S)-7-[(R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-carboxylic acid |
| (6R,7S)-zingiberene |
| (6R,7S)-7-((R)-2-amino-2-phenylacetamido)-3-chloro-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid |