CAS 76470-66-1|loracarbef

Introduction:Basic information about CAS 76470-66-1|loracarbef, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Nameloracarbef
CAS Number76470-66-1Molecular Weight349.76900
Density1.52g/cm3Boiling Point662.2ºC at 760 mmHg
Molecular FormulaC16H16ClN3O4Melting Point/
MSDS/Flash Point354.3ºC

Names

Nameloracarbef
SynonymMore Synonyms

loracarbef BiologicalActivity

DescriptionLoracarbef (Lorabid), a cephalosporin antibiotic, is an orally active second-generation synthetic beta-lactam antibiotic of the carbacephem class[1][2].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial
In VitroLoracarbef (Lorabid) demonstrates excellent activity against isolates of Escherichia coli and Klebsiella, Proteus and Salmonella species[2].
References

[1]. M Hu, et al. Mechanisms of Transport of Quinapril in Caco-2 Cell Monolayers: Comparison With Cephalexin. Pharm Res. 1995 Aug;12(8):1120-5.

[2]. J W Dyke, et al. Antimicrobial Activity of New Antibiotics Against Bacterial Isolates From a Community Hospital. Chemotherapy. Sep-Oct 1993;39(5):315-21.

Chemical & Physical Properties

Density1.52g/cm3
Boiling Point662.2ºC at 760 mmHg
Molecular FormulaC16H16ClN3O4
Molecular Weight349.76900
Flash Point354.3ºC
Exact Mass349.08300
PSA112.73000
LogP1.73990
Index of Refraction1.677
InChIKeyJAPHQRWPEGVNBT-UTUOFQBUSA-N
SMILESNC(C(=O)NC1C(=O)N2C(C(=O)O)=C(Cl)CCC12)c1ccccc1

Synonyms

(6R,7S)-1,3,10-bisabolatriene
5-(1,5-dimethyl-4-hexenyl)-2-methyl-1,3-cyclohexadiene
(-)-(4S,7S)-zingiberene
(6R,7S)-7-[(R)-2-amino-2-phenylacetamido]-3-chloro-8-oxo-1-azabicyclo[4.2.0]oct-2-ene-carboxylic acid
(6R,7S)-zingiberene
(6R,7S)-7-((R)-2-amino-2-phenylacetamido)-3-chloro-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
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