CAS 100-55-0|Nicotinyl alcohol
| Common Name | Nicotinyl alcohol | ||
|---|---|---|---|
| CAS Number | 100-55-0 | Molecular Weight | 109.126 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 266.0±0.0 °C at 760 mmHg |
| Molecular Formula | C6H7NO | Melting Point | -7 °C |
| MSDS | ChineseUSA | Flash Point | 97.5±20.4 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 3-Pyridinemethanol |
|---|---|
| Synonym | More Synonyms |
Nicotinyl alcohol BiologicalActivity
| Description | 3-Pyridinemethanol (Nicotinyl alcohol), a pyridine derivative, is a cholesterol-lowering agent[1][2]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
| References | [1]. Heiberg A. Nikotinyl-alkohol som kolesterolsenkende medikament [Nicotinyl alcohol as a cholesterol-lowering agent]. Nord Med. 1969;81(22):698-700. [2]. Gargaun S, et al. A novel method aimed at counteracting the side effects caused by prostaglandin e2 deficiency during non-steroidal anti-inflammatory drug therapy. Antiinflamm Antiallergy Agents Med Chem. 2014;13(2):121-127. |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 266.0±0.0 °C at 760 mmHg |
| Melting Point | -7 °C |
| Molecular Formula | C6H7NO |
| Molecular Weight | 109.126 |
| Flash Point | 97.5±20.4 °C |
| Exact Mass | 109.052765 |
| PSA | 33.12000 |
| LogP | -0.46 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.551 |
| InChIKey | MVQVNTPHUGQQHK-UHFFFAOYSA-N |
| SMILES | OCc1cccnc1 |
| Storage condition | 2-8°C |
| Water Solubility | soluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 11,242,1956
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 22,483,1962
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36/38 |
| Safety Phrases | S26-S36-S24/25 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| RTECS | UT4690000 |
| HS Code | 29333999 |
Customs
| HS Code | 2933399090 |
|---|---|
| Summary | 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles25
More Articles| Inhibitory effects of niacin and its analogues on induction of ornithine decarboxylase activity by diethylnitrosamine in rat liver. Biochem. Pharmacol. 36(18) , 3015-9, (1987) Pharmacological doses of niacin and its analogues were given intraperitoneally to rats with and without coadministration of a hepatocarcinogenic dose of diethylnitrosamine (DEN), and their effects on ... | |
| The role of p53 in the cellular toxicity by active trans-platinum complexes containing isopropylamine and hydroxymethylpyridine. Eur. J. Med. Chem. 45(1) , 134-41, (2010) Despite some initial research that reported a lack of activity of trans geometry, complexes with general formula trans-[PtCl2(L)(L')] exhibit an important cytotoxic activity in cisplatin-sensitive and... | |
| Oxidation of alcohols using a manganese (II) complex based on a pentakis benzimidazole amide ligand. Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 74(2) , 536-43, (2009) A pentakis benzimidazole based penta-amide ligand diethylenetriamine-N,N,N',N',N''-pentakis(2-methyl benzimidazolyl)penta-amide [GBDTPA] has been synthesized and utilized to prepare Mn (II) complexes ... |
Synonyms
| (Pyridin-3-yl)methanol |
| 3-Pyridylmethanol |
| pyridylcarbinol |
| pyridin-3-ylmethanol |
| 3-Pyridinylmethanol |
| b-Pyridinecarbinol |
| 3-PYRIDINYLCARBINOL |
| 3-hydroxymethylpyridine |
| β-Pyridinecarbinol |
| 3-Pyridinemethanol |
| pyridine, 3-(hydroxymethyl)- |
| 3-(Hydroxymethyl)pyridine |
| EINECS 202-864-6 |
| Nicotinyl alcohol |
| β-Picolyl alcohol |
| Pyridylmethanol |
| MFCD00006407 |
| RO 1-5155 |
| b-Pyridylcarbinol |
| β-Pyridylcarbinol |
| b-Picolyl Alcohol |
