Introduction：Basic information about CAS 57717-80-3|CGP 7930, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | CGP 7930 |
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| CAS Number | 57717-80-3 | Molecular Weight | 292.45600 |
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| Density | 0.971g/cm3 | Boiling Point | 364.7ºC at 760mmHg |
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| Molecular Formula | C19H32O2 | Melting Point | / |
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| MSDS | / | Flash Point | 152.6ºC |
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Names
| Name | 3-(3,5-ditert-butyl-4-hydroxyphenyl)-2,2-dimethyl-1-propanol |
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| Synonym | More Synonyms |
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CGP 7930 BiologicalActivity
| Description | CGP7930 (3-(3’,5’-Di-tert-butyl-4’-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. CGP7930 enhances the inhibitory effect of l-baclofen on the oscillatory activity of cultured cortical neurons[1]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>GABA ReceptorResearch Areas >>Neurological DiseaseSignaling Pathways >>Neuronal Signaling >>GABA Receptor |
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| References | [1]. Urwyler S, et al. Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol Pharmacol. 2001; 60(5):963-71. |
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Chemical & Physical Properties
| Density | 0.971g/cm3 |
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| Boiling Point | 364.7ºC at 760mmHg |
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| Molecular Formula | C19H32O2 |
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| Molecular Weight | 292.45600 |
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| Flash Point | 152.6ºC |
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| Exact Mass | 292.24000 |
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| PSA | 40.46000 |
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| LogP | 4.54820 |
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| InChIKey | XLWJPQQFJNGUPA-UHFFFAOYSA-N |
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| SMILES | CC(C)(CO)Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1 |
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Safety Information
Synonyms
