Introduction:Basic information about CAS 113731-96-7|RFARKGALRQKNVHEVKN, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | RFARKGALRQKNVHEVKN |
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| CAS Number | 113731-96-7 | Molecular Weight | 2151.48 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C93H159N35O24 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | pkc (19-36) |
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| Synonym | More Synonyms |
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RFARKGALRQKNVHEVKN BiologicalActivity
| Description | Protein Kinase C (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (PKC), with an IC50 of 0.18 μM. Protein Kinase C (19-36) markedly attenuated vascular hyperproliferation and hypertrophy as well as glucose-induced suppression of natriuretic peptide receptor response[1]. |
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| Related Catalog | Signaling Pathways >>Epigenetics >>PKCResearch Areas >>OthersSignaling Pathways >>TGF-beta/Smad >>PKC |
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| Target | IC50: 0.18 μM (protein kinase C)[1]. |
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| References | [1]. Yasunari K, et al. Possible involvement of phospholipase D and protein kinase C in vascular growth induced by elevated glucose concentration. Hypertension. 1996 Aug;28(2):159-68. |
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Chemical & Physical Properties
| Molecular Formula | C93H159N35O24 |
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| Molecular Weight | 2151.48 |
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| Exact Mass | 2150.23000 |
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| PSA | 1017.03000 |
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| LogP | 4.05580 |
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| InChIKey | NHCJMYZDRROLEW-UHFFFAOYSA-N |
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| SMILES | CC(C)CC(NC(=O)C(C)NC(=O)CNC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(Cc1ccccc1)NC(=O)C(N)CCCNC(=N)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(N)=O)C(=O)NC(CCCCN)C(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(Cc1c[nH]cn1)C(=O)NC(CCC(=O)O)C(=O)NC(C(=O)NC(CCCCN)C(=O)NC(CC(N)=O)C(=O)O)C(C)C)C(C)C |
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Safety Information
Synonyms
| protein kinase c selective inhibitor |
| protein kinase c fragment |
| protein kinase c fragment 19-36 |
| pkc selective inhibitor protein |
| rfarkgalrqknvhevkn |
| pkc selective inhibitor |
| h2n-rfarkgalrqknvhevkn-oh |
| pkc 19-36 |