CAS 460-35-5|3-chloro-1,1,1-trifluoropropane

Introduction：Basic information about CAS 460-35-5|3-chloro-1,1,1-trifluoropropane, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Safety Information
5. Customs
6. Synonyms

Common Name	3-chloro-1,1,1-trifluoropropane
CAS Number	460-35-5	Molecular Weight	132.512
Density	1.3±0.1 g/cm3	Boiling Point	44.1±8.0 °C at 760 mmHg
Molecular Formula	C₃H₄ClF₃	Melting Point	-106.2℃
MSDS	USA	Flash Point	-6.8±10.4 °C

Names

Name	3-Chloro-1,1,1-trifluoropropane
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	44.1±8.0 °C at 760 mmHg
Melting Point	-106.2℃
Molecular Formula	C₃H₄ClF₃
Molecular Weight	132.512
Flash Point	-6.8±10.4 °C
Exact Mass	131.995361
LogP	1.55
Vapour Pressure	380.2±0.1 mmHg at 25°C
Index of Refraction	1.324
InChIKey	ZPIFKCVYZBVZIV-UHFFFAOYSA-N
SMILES	FC(F)(F)CCCl

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TX6200000

CHEMICAL NAME :: Propane, 3-chloro-1,1,1-trifluoro-

CAS REGISTRY NUMBER :: 460-35-5

BEILSTEIN REFERENCE NO. :: 1734941

LAST UPDATED :: 199701

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C3-H4-Cl-F3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1800 mg/m3/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,115,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 62 mg/kg

TOXIC EFFECTS :: Behavioral - sleep Behavioral - somnolence (general depressed activity) Behavioral - ataxia

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 28(12),9,1963

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/m3/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,115,1982

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 2300 mg/m3/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,115,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1062 mg/kg/30W-I

TOXIC EFFECTS :: Behavioral - alteration of classical conditioning

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 28(12),9,1963

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1062 mg/kg/30W-I

TOXIC EFFECTS :: Blood - change in clotting factors Blood - other changes

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 28(12),9,1963

Safety Information

Hazard Codes	Xi: Irritant;
Risk Phrases	22-36
Safety Phrases	23-24/25-26
HS Code	2903791090

Customs

HS Code	2903791090
Summary	2903791090 halogenated derivatives of methane, ethane or propane (hcfcs)only with fluorine and chlorine。supervision conditions:14xy(import license,export license,export license,export license)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

Synonyms

EINECS 207-307-0

3-chloro-1,1,1-trifluoropropane

1,1,1-Trifluoro-3-chloropropane

Propane, 3-chloro-1,1,1-trifluoro-

HCFC-253fb

MFCD00069094

Recommended......