Introduction:Basic information about CAS 15176-29-1|Edoxudine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Edoxudine |
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| CAS Number | 15176-29-1 | Molecular Weight | 256.25500 |
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| Density | 1.389 g/cm3 | Boiling Point | / |
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| Molecular Formula | C11H16N2O5 | Melting Point | 152-153° |
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| MSDS | USA | Flash Point | / |
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Names
| Name | 5-ethyl-2'-deoxyuridine |
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| Synonym | More Synonyms |
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Edoxudine BiologicalActivity
| Description | Edoxudine is an antiviral drug, is an analog of thymidine, shows effectiveness against herpes simplex virus. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection |
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Chemical & Physical Properties
| Density | 1.389 g/cm3 |
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| Melting Point | 152-153° |
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| Molecular Formula | C11H16N2O5 |
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| Molecular Weight | 256.25500 |
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| Exact Mass | 256.10600 |
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| PSA | 104.55000 |
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| Index of Refraction | 1.569 |
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| InChIKey | XACKNLSZYYIACO-DJLDLDEBSA-N |
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| SMILES | CCc1cn(C2CC(O)C(CO)O2)c(=O)[nH]c1=O |
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| Storage condition | ?20°C |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- YU7500000
- CHEMICAL NAME :
- Uridine, 2'-deoxy-5-ethyl-
- CAS REGISTRY NUMBER :
- 15176-29-1
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C11-H16-N2-O5
- MOLECULAR WEIGHT :
- 256.29
- WISWESSER LINE NOTATION :
- T6NVMVJ F2 A- BT5OTJ E1Q
HEALTH HAZARD DATAACUTE TOXICITY DATAMUTATION DATA - TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Rodent - rabbit Kidney
- DOSE/DURATION :
- 200 mg/L
- REFERENCE :
- BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 24,1073,1975
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | YU7500000 |
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| HS Code | 29349990 |
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Articles26
More Articles
| Sensitivity of monkey B virus (Cercopithecine herpesvirus 1) to antiviral drugs: role of thymidine kinase in antiviral activities of substrate analogs and acyclonucleosides. Antimicrob. Agents Chemother. 51 , 2028-34, (2007) Herpes B virus (B virus [BV]) is a macaque herpesvirus that is occasionally transmitted to humans where it can cause rapidly ascending encephalitis that is often fatal. To understand the low susceptib... | |
| Pleiotrophin suppression of receptor protein tyrosine phosphatase-β/ζ maintains the self-renewal competence of fetal human oligodendrocyte progenitor cells. J. Neurosci. 32(43) , 15066-75, (2012) Oligodendrocyte progenitor cells (OPCs) persist in human white matter, yet the mechanisms by which they are maintained in an undifferentiated state are unknown. Human OPCs differentially express prote... | |
| An in vitro study of ophthalmic antiviral agent toxicity on rabbit corneal epithelium. Antiviral Res. 9(4) , 263-72, (1988) Using an in vitro system we measured the corneal epithelial cytotoxicity and the antiviral activity of the antiviral agents idoxuridine (IDU), trifluridine (TFT), ethyldeoxyuridine (EDU), and (E)-5-(2... | |
Synonyms
| 5-Ethyl-2'-deoxyuridine |
| 2'-deoxy-5-ethyluridine |
| EUdR Edoxudine |
| edu |
| edoxudin |
| Etudr |
| 5-Ethyl-durd |
| aedurid |
| 5-ethyldeoxyuridine |
| EDOXUDINE |