CAS 3680-02-2|Methyl Vinyl sulphone
| Common Name | Methyl Vinyl sulphone | ||
|---|---|---|---|
| CAS Number | 3680-02-2 | Molecular Weight | 90.144 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 201.2±13.0 °C at 760 mmHg |
| Molecular Formula | C3H6OS | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 75.5±19.8 °C |
| Symbol | GHS05, GHS06 | Signal Word | Danger |
Names
| Name | Methyl vinyl sulfone |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 201.2±13.0 °C at 760 mmHg |
| Molecular Formula | C3H6OS |
| Molecular Weight | 90.144 |
| Flash Point | 75.5±19.8 °C |
| Exact Mass | 90.013931 |
| PSA | 42.52000 |
| LogP | -0.73 |
| Vapour Pressure | 0.4±0.4 mmHg at 25°C |
| Index of Refraction | 1.505 |
| Storage condition | 0-6°C |
| Stability | Stable. Incompatible with strong oxidizing agents. Irritant. |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 570 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 32 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA - TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 1 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 245,191,1990
- TYPE OF TEST :
- Sex chromosome loss and nondisjunction
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 1 mg/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 245,191,1990
Safety Information
| Symbol | GHS05, GHS06 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H310-H318 |
| Precautionary Statements | P280-P302 + P350-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | T+:Verytoxic; |
| Risk Phrases | R22;R27;R41 |
| Safety Phrases | S26-S28-S36/37/39-S45-S28A |
| RIDADR | UN 2810 6.1/PG 1 |
| WGK Germany | 3 |
| RTECS | WR6825000 |
| Packaging Group | II |
| Hazard Class | 6.1 |
| HS Code | 2904100000 |
Customs
| HS Code | 2904100000 |
|---|---|
| Summary | 2904100000 derivatives containing only sulpho groups, their salts and ethyl esters。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
Articles10
More Articles| Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway. Oncotarget 5(14) , 5559-69, (2014) Usp5 is a deubiquitinase (DUB) previously shown to regulate unanchored poly-ubiquitin (Ub) chains, p53 transcriptional activity and double-strand DNA repair. In BRAF mutant melanoma cells, Usp5 activi... | |
| Protein reactions with methyl and ethyl vinyl sulfones. J. Protein Chem. 7(1) , 49-54, (1988) Disulfide bonds of bovine serum albumin and wool were reduced by n-tributylphosphine to sulfhydryl groups that were then modified by methyl or ethyl vinyl sulfone in a nucleophilic addition reaction t... | |
| Trypanocidal activities of trileucine methyl vinyl sulfone proteasome inhibitors. Parasitol. Res. 95(1) , 73-6, (2005) Previous studies have shown that proteasome inhibitors are novel agents for chemotherapy of human African trypanosomiasis or sleeping sickness. In this study, five peptide trileucine methyl vinyl sulf... |
Synonyms
| 1-methylsulfonylethene |
| EINECS 222-958-0 |
| MFCD00007567 |
| Ethene, (methylsulfinyl)- |
| (Methylsulfinyl)ethene |
| Methyl vinyl sulfoxide |
| Sulfoxide, methyl vinyl |
| Methyl Vinyl sulphone |
