CAS 83534-39-8|PNGase F
| Common Name | PNGase F | ||
|---|---|---|---|
| CAS Number | 83534-39-8 | Molecular Weight | / |
| Density | / | Boiling Point | / |
| Molecular Formula | / | Melting Point | / |
| MSDS | USA | Flash Point | / |
| Symbol | GHS05, GHS06, GHS09 | Signal Word | Danger |
Names
| Name | Glycoamidase F |
|---|---|
| Synonym | More Synonyms |
PNGase F BiologicalActivity
| Description | PNGase F, a glycosidase, catalyzes the cleavage of an internal glycoside bond in an oligosaccharide. PNGase F removes nearly all N-linked oligosaccharides from glycoproteins[1][2]. |
|---|---|
| Related Catalog | Research Areas >>Cancer |
| In Vitro | PNGase F 可以在糖分析工作流程中从糖蛋白中释放 N-聚糖[1]。 |
| References | [1]. Vilaj M, et al. Evaluation of different PNGase F enzymes in immunoglobulin G and total plasma N-glycans analysis. Glycobiology. 2021 Jan 9;31(1):2-7. [2]. Huang J, et al. Highly Efficient Release of Glycopeptides from Hydrazide Beads by Hydroxylamine Assisted PNGase F Deglycosylation for N-Glycoproteome Analysis. Anal Chem. 2015 Oct 20;87(20):10199-204. |
Chemical & Physical Properties
| InChIKey | UVVLNLNAGIIHGJ-UHFFFAOYSA-N |
|---|---|
| SMILES | Cc1cnc2c(c1)C(=O)N(C1CCC(=O)NC1=O)C2.Cc1cnc2c(c1)C(=O)N(C1CCC(=O)NC1=O)C2=O.Cc1cnc2c(c1)CN(C1CCC(=O)NC1=O)C2=O.Cc1cnc2c(c1F)CN(C1CCC(=O)NC1=O)C2=O.Cc1cnc2c(n1)C(=O)N(C1CCC(=O)NC1=O)C2.Cc1cnc2c(n1)C(=O)N(C1CCC(=O)NC1=O)C2=O.Cc1cnc2c(n1)CN(C1CCC(=O)NC1=O)C2=O.Cc1ncc2c(n1)CN(C1CCC(=O)NC1=O)C2=O |
| Storage condition | 20°C |
Safety Information
| Symbol | GHS05, GHS06, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H311-H317-H318-H410 |
| Precautionary Statements | P273-P280-P305 + P351 + P338-P312-P501 |
| Personal Protective Equipment | Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US) |
| Hazard Codes | Xi,N,Xn |
| Risk Phrases | 37/38-41-50/53-43-20/21/22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
Articles48
More Articles| The characterization and quantitation of glycomic changes in CHO cells during a bioreactor campaign. Biotechnol. Bioeng. 109(12) , 3007-17, (2012) Within the biotechnology industry there is a continuous drive to better and more fully understand the biopharmaceutical process in order to achieve better process control. A method to monitor and quan... | |
| N-Terminal signal sequence is required for cellular trafficking and hyaluronan-depolymerization of KIAA1199. FEBS Lett. 588(1) , 111-6, (2014) Recently, we disclosed that KIAA1199-mediated hyaluronan (HA) depolymerization requires an acidic cellular microenvironment (e.g. clathrin-coated vesicles or early endosomes), but no information about... | |
| Liver and muscle hemojuvelin are differently glycosylated. BMC Biochem. 12 , 52, (2011) Hemojuvelin (HJV) is one of essential components for expression of hepcidin, a hormone which regulates iron transport. HJV is mainly expressed in muscle and liver, and processing of HJV in both tissue... |
Synonyms
| glycopeptidase |
| glycopeptidase f |
| glycopeptidase a |
| n-glycanase(r) |
| n-glycosidase a |
| ec 3.5.1.52 |
| n-glycanase |
| MFCD00131222 |
| n-linked-glycopeptide-[n-acetyl-beta-d-glucosaminyl]-l-asparagine amidohydrolase |
