CAS 9015-68-3|asparaginase
| Common Name | asparaginase | ||
|---|---|---|---|
| CAS Number | 9015-68-3 | Molecular Weight | 151.186 |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 204.5±23.0 °C at 760 mmHg |
| Molecular Formula | C7H5NOS | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 77.5±22.6 °C |
| Symbol | GHS07, GHS08 | Signal Word | Warning |
Names
| Name | L-Asparaginase |
|---|---|
| Synonym | More Synonyms |
asparaginase BiologicalActivity
| Description | L-Asparaginase (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment. L-Asparaginase depletes L-asparagine from plasma resulting in inhibition of RNA and DNA synthesis with the subsequent blastic cell apoptosis[1]. |
|---|---|
| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
| References | [1]. Piatkowska-Jakubas B, et al. Use of L-asparaginase in acute lymphoblastic leukemia: recommendations of the Polish Adult Leukemia Group. Pol Arch Med Wewn. 2008 Nov;118(11):664-9. |
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 204.5±23.0 °C at 760 mmHg |
| Molecular Formula | C7H5NOS |
| Molecular Weight | 151.186 |
| Flash Point | 77.5±22.6 °C |
| Exact Mass | 151.009186 |
| LogP | 1.78 |
| Vapour Pressure | 0.2±0.4 mmHg at 25°C |
| Index of Refraction | 1.745 |
| Storage condition | 2-8°C |
Safety Information
| Symbol | GHS07, GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H317-H361 |
| Precautionary Statements | P280 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T,Xn |
| Risk Phrases | 61-42/43-63 |
| Safety Phrases | 53-22-36/37/39-45-36/37 |
| RIDADR | 3249 |
| WGK Germany | 3 |
| RTECS | CI9000000 |
| Packaging Group | II |
Articles64
More Articles| Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet. 36 , 40-5, (2004) As a base for human transcriptome and functional genomics, we created the "full-length long Japan" (FLJ) collection of sequenced human cDNAs. We determined the entire sequence of 21,243 selected clone... | |
| The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. 14 , 2121-7, (2004) The National Institutes of Health's Mammalian Gene Collection (MGC) project was designed to generate and sequence a publicly accessible cDNA resource containing a complete open reading frame (ORF) for... | |
| Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. Anal. Chem. 81(11) , 4493-501, (2009) The analysis of proteome-wide phosphorylation events is still a major analytical challenge because of the enormous complexity of protein phosphorylation networks. In this work, we evaluate the complem... |
Synonyms
| IUB: 3.5.4.4 |
| Benzisothiazolone |
| L-ASPARAGINASE |
| T56 BSMVJ |
| ASPARAGINASE |
| benzo[d]isothiazol-3-one |
| 1,2-Benzisothiazol-3(2H)-one |
| EC 3.5.1.1 |
| T56 BSNJ DQ |
| crasnitin |
| L-ASPARAGINE AMIDOHYDROLASE |
| 1,2-Benzothiazol-3(2H)-one |
| elspar |
| 1,2-Benzisothiazol-3-ol |
| 1,2-Benzothiazol-3-ol |
| Benzisothiazolone (BIT) |
| colaspase |
