Introduction：Basic information about CAS 22467-07-8|Gymnemagenin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Gymnemagenin |
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| CAS Number | 22467-07-8 | Molecular Weight | 506.714 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 634.5±55.0 °C at 760 mmHg |
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| Molecular Formula | C30H50O6 | Melting Point | 330-331℃ |
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| MSDS | USA | Flash Point | 262.0±26.1 °C |
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Names
| Name | protoaescigenin |
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| Synonym | More Synonyms |
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Gymnemagenin BiologicalActivity
| Description | Gymnemagenin is a triterpenoid isolated from G. sylvestre. Gymnemagenin is an agent for diabetes and obesity and also possesses antiviral properties[1][2]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
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| In Vivo | Gymnemagenin has a poor oral bioavailability (~ 14 %) in rats[2]. Gymnemagenin has a short half-life and a high clearance in rats[2]. Gymnemagenin metabolizes rapidly with a short apparent and intrinsic half-life (~ 7 min) and high intrinsic clearance[2]. |
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| References | [1]. Parthasarathy R, et al. Gymnemagenin-producing endophytic fungus isolated from a medicinal plant Gymnema sylvestre R.Br. Appl Biochem Biotechnol. 2014 Mar;172(6):3141-52. [2]. In Vitro Metabolic Stability and Permeability of Gymnemagenin and Its In Vivo Pharmacokinetic Correlation in Rats - A Pilot Study. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 634.5±55.0 °C at 760 mmHg |
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| Melting Point | 330-331℃ |
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| Molecular Formula | C30H50O6 |
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| Molecular Weight | 506.714 |
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| Flash Point | 262.0±26.1 °C |
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| Exact Mass | 506.360748 |
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| PSA | 121.38000 |
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| LogP | 3.98 |
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| Vapour Pressure | 0.0±4.2 mmHg at 25°C |
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| Index of Refraction | 1.598 |
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| InChIKey | VKJLHZZPVLQJKG-ABHKXHSUSA-N |
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| SMILES | CC1(C)CC2C3=CCC4C5(C)CCC(O)C(C)(CO)C5CCC4(C)C3(C)CC(O)C2(CO)C(O)C1O |
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Safety Information
| RIDADR | NONH for all modes of transport |
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Synonyms
| Protoaescigenin |
| Olean-12-ene-3,16,21,22,23,28-hexol, (3β,16β,21β,22α)- |
| (3β,16β,21β,22α)-Olean-12-ene-3,16,21,22,23,28-hexol |
| Gymnemagenin |
