Introduction：Basic information about CAS 29220-16-4|Dehydrotrametenolic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Dehydrotrametenolic acid |
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| CAS Number | 29220-16-4 | Molecular Weight | 454.684 |
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| Density | 1.08±0.1 g/cm3 | Boiling Point | 585.4±50.0 °C at 760 mmHg |
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| Molecular Formula | C30H46O3 | Melting Point | 257-259 ºC |
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| MSDS | / | Flash Point | 321.9±26.6 °C |
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Names
| Name | dehydrotrametenolic acid |
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| Synonym | More Synonyms |
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Dehydrotrametenolic acid BiologicalActivity
| Description | 3-Dehydrotrametenolic acid, isolated from the sclerotium of Poria cocos, is a lactate dehydrogenase (LDH) inhibitor. 3-Dehydrotrametenolic acid promotes adipocyte differentiation in vitro and acts as an insulin sensitizer in vivo. 3-Dehydrotrametenolic acid induces apoptosis and has anticancer activity[1][2]. |
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| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>CancerSignaling Pathways >>Metabolic Enzyme/Protease >>Lactate Dehydrogenase |
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| Target | Lactate dehydrogenase [1] |
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| References | [1]. De Nicola GR, et al. Novel gram-scale production of enantiopure R-sulforaphane from Tuscan black kale seeds. Molecules. 2014 May 27;19(6):6975-86. [2]. Abdull Razis AF, et al. The natural chemopreventive phytochemical R-sulforaphane is a far more potent inducer of the carcinogen-detoxifying enzyme systems in rat liver and lung than the S-isomer. Int J Cancer. 2011 Jun 15;128(12):2775-82. |
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Chemical & Physical Properties
| Density | 1.08±0.1 g/cm3 |
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| Boiling Point | 585.4±50.0 °C at 760 mmHg |
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| Melting Point | 257-259 ºC |
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| Molecular Formula | C30H46O3 |
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| Molecular Weight | 454.684 |
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| Flash Point | 321.9±26.6 °C |
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| Exact Mass | 454.344696 |
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| PSA | 57.53000 |
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| LogP | 8.50 |
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| Vapour Pressure | 0.0±3.7 mmHg at 25°C |
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| Index of Refraction | 1.557 |
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| InChIKey | QFPLAAZRZNKRRY-UHFFFAOYSA-N |
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| SMILES | CC(C)=CCCC(C(=O)O)C1CCC2(C)C3=CCC4C(C)(CCC(O)C4(C)C)C3=CCC12C |
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| Storage condition | 2-8℃ |
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| Water Solubility | Insuluble (1.0E-5 g/L) (25 ºC) |
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Synonyms
| 3β-hydroxylanosta-7,9(11)24-trien-21-oic acid |
| 3-epidehydrotrametenolic |
| 3-epi-dehydrotrametenolic acid |
| 3β-hydroxylanosta-7,9(11),24-trien-21-oic acid |
| 3-epidehydrotrametenolic acid |
| (3β)-3-Hydroxylanosta-7,9(11),24-trien-21-oic acid |
| Lanosta-7,9(11),24-trien-21-oic acid, 3-hydroxy-, (3β)- |
| 3beta-Hydroxylanosta-7,9(11),24-trien-21-oic acid |
