CAS 9014-01-1|Subtilisin (Compound proteinase)
| Common Name | Subtilisin (Compound proteinase) | ||
|---|---|---|---|
| CAS Number | 9014-01-1 | Molecular Weight | 238.19786 |
| Density | 1.3 | Boiling Point | / |
| Molecular Formula | C11H9N3O2.Na | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | / |
| Symbol | GHS05, GHS07, GHS08, GHS09 | Signal Word | Danger |
Names
| Name | Casein |
|---|---|
| Synonym | More Synonyms |
Subtilisin (Compound proteinase) BiologicalActivity
| Description | Subtilisin Compound proteinase (Protamex) is a proteolytic enzyme. Subtilisin Compound proteinase has catalytic activity in anhydrous dimethyl formamide. Subtilisin Compound proteinase can be used as a catalyst for easy coupling between sugars and amino acids[1][2]. |
|---|---|
| Related Catalog | Research Areas >>Others |
| In Vitro | Subtilisin Compound proteinase 在二甲基甲酰胺中选择性的酰化二糖、寡糖、核苷和相关的大分子[1]。 Subtilisin Compound proteinase 在活化的丁酸三氟乙酯 (TFEB) 存在下，可以酰化黄烷醇异槲皮素 (1) 的 D-葡萄糖[3]。 Subtilisin Compound proteinase 改善了蛋白质和脂肪酸的溶解度，恢复了多肽和不饱和脂肪酸[4]。 |
| In Vivo | Subtilisin Compound proteinase 水解产物 (150 mg/kg 和 300 mg/kg；口服；一天一次持续 6 周) (≤1 kDa 的葡糖乳蛋白水解物，MLPH) 对 ob/ob 小鼠具有抗肥胖和抗高血糖作用[4]。 |
| References | [1]. Riva S, et al. Protease-catalyzed regioselective esterification of sugars and related compounds in anhydrous dimethylformamide[J]. Journal of the American Chemical Society, 1988, 110(2): 584-589. [2]. Philipp M, et al. Inhibition of subtilisin by substituted arylboronic acids. FEBS Lett. 1981 Oct 12;133(1):36-8. [3]. Danieli B, et al. On the regioselectivity of the protease subtilisin towards the acylation of enantiomeric pairs of benzyl and naphthyl glycopyranosides. Part 2[J]. Tetrahedron, 1999, 55(7): 2045-2060. [4]. Kim MJ, et al. Anti-Obesity and Anti-Hyperglycemic Effects of Meretrix lusoria Protamex Hydrolysate in ob/ob Mice. Int J Mol Sci. 2022 Apr 5;23(7):4015. |
Chemical & Physical Properties
| Density | 1.3 |
|---|---|
| Molecular Formula | C11H9N3O2.Na |
| Molecular Weight | 238.19786 |
| Appearance of Characters | powder | white |
| Storage condition | 2-8°C |
| Stability | store cold |
Safety Information
| Symbol | GHS05, GHS07, GHS08, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H315-H318-H334-H335-H410 |
| Precautionary Statements | P261-P273-P280-P305 + P351 + P338-P342 + P311 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn,N |
| Risk Phrases | 37/38-41-42-36/37/38-50-22 |
| Safety Phrases | 23-24-26-36/37/39-22-36/37-61-45-39 |
| RIDADR | 3082 |
| WGK Germany | 2 |
| RTECS | UK9540000 |
| HS Code | 35079090 |
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Synonyms
| MFCD00132092 |
| EINECS 232-752-2 |
