CAS 7672-27-7|N'-Nitro-L-arginine benzyl ester

Introduction:Basic information about CAS 7672-27-7|N'-Nitro-L-arginine benzyl ester, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameN'-Nitro-L-arginine benzyl ester
CAS Number7672-27-7Molecular Weight309.32
Density1.37Boiling Point456.8±55.0 °C(Predicted)
Molecular FormulaC13H19N5O4Melting Point132-134 ºC
MSDS/Flash Point/

Names

NameArg(NO2)-OBzl
SynonymMore Synonyms

N'-Nitro-L-arginine benzyl ester BiologicalActivity

DescriptionL-NABE is a nitric oxide (NO) synthase inhibitor. L-NABE is also a potent endothelium dependent vasoconstrictor and inhibitor of relaxation[1][2].
Related CatalogResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>Immunology/Inflammation >>NO Synthase
References

[1]. Nossaman BD, et al. Nomega-Nitro-L-Arginine Benzyl Ester Enhances Pulmonary Vasopressor Responses to Hypoxia and to Angiotensin II. Am J Ther. 1995 Jul;2(7):462-468.  

[2]. G Thomas, et al. NW-nitro L-arginine benzyl ester, a potent irreversible inhibitor of endothelium dependent relaxation. Biochem Biophys Res Commun. 1991 Sep 30;179(3):1677-82.  

Chemical & Physical Properties

Density1.37
Boiling Point456.8±55.0 °C(Predicted)
Melting Point132-134 ºC
Molecular FormulaC13H19N5O4
Molecular Weight309.32
Exact Mass309.14400
PSA146.05000
LogP2.24800
InChIKeyFAJFGLZHUIUNSS-NSHDSACASA-N
SMILESNC(=NCCCC(N)C(=O)OCc1ccccc1)N[N+](=O)[O-]
Storage condition2-8°C

Safety Information

Hazard CodesXn

Synonyms

Nω-nitro-L-arginine benzyl ester
Ng-nitro-L-arginine benzyl ester
Nε-Nitro-L-arginin-benzylester
N'-Nitro-L-arginine benzyl ester
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