CAS 173379-73-2|4'-C-azido-2'-deoxy-2'-fluoro-beta-D-arabinouridine

Introduction:Basic information about CAS 173379-73-2|4'-C-azido-2'-deoxy-2'-fluoro-beta-D-arabinouridine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name4'-C-azido-2'-deoxy-2'-fluoro-beta-D-arabinouridine
CAS Number173379-73-2Molecular Weight287.20
Density/Boiling Point/
Molecular FormulaC9H10FN5O5Melting Point/
MSDS/Flash Point/

Names

Name1-[(2R,3S,4R,5R)-5-Azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione
SynonymMore Synonyms

BiologicalActivity

Description4’-Azido-2’-deoxy-2’-fluoro-beta-D-arabinouridine is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
Related CatalogSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others
References

[1]. Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.  

Chemical & Physical Properties

Molecular FormulaC9H10FN5O5
Molecular Weight287.20
Exact Mass287.066589
PSA154.30000
LogP-0.27
InChIKeySNWCOSVWPQSOEU-XZMZPDFPSA-N
SMILES[N-]=[N+]=NC1(CO)OC(n2ccc(=O)[nH]c2=O)C(F)C1O

Synonyms

1-[(2R,3S,4R,5R)-5-Azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-2,4(1H,3H)-pyrimidinedione
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