Introduction：Basic information about CAS 50980-32-0|ankaflavin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | ankaflavin |
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| CAS Number | 50980-32-0 | Molecular Weight | 386.48100 |
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| Density | 1.15±0.1 g/cm3(Predicted) | Boiling Point | 590.7±50.0 °C(Predicted) |
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| Molecular Formula | C23H30O5 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | ankaflavin |
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| Synonym | More Synonyms |
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ankaflavin BiologicalActivity
| Description | Ankaflavin, isolated from Monascus-Fermented red rice, is a PPARγ agonist with anti-inlfammatory activity. Ankaflavin exhibits selective cytotoxic effect and induces cell death on cancer cells[1][2]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>PPARResearch Areas >>Inflammation/Immunology |
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| Target | PPARγ[2]. |
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| References | [1]. Su NW, et al. Ankaflavin from Monascus-fermented red rice exhibits selective cytotoxic effect and induces cell death on Hep G2 cells. J Agric Food Chem. 2005 Mar 23;53(6):1949-54. [2]. Lee BH, et al. Ankaflavin: a natural novel PPARγ agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo. Free Radic Biol Med. 2012 Dec 1;53(11):2008-16. |
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Chemical & Physical Properties
| Density | 1.15±0.1 g/cm3(Predicted) |
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| Boiling Point | 590.7±50.0 °C(Predicted) |
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| Molecular Formula | C23H30O5 |
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| Molecular Weight | 386.48100 |
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| Exact Mass | 386.20900 |
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| PSA | 69.67000 |
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| LogP | 4.22350 |
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| InChIKey | AQTJNEHGKRUSLT-ODTNPMSZSA-N |
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| SMILES | CC=CC1=CC2=C(CO1)C(=O)C1(C)OC(=O)C(C(=O)CCCCCCC)C1C2 |
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Synonyms
| Ankaflavin |
| (3S,3aR,9aR)-9a-Methyl-3-octanoyl-6-((E)-propenyl)-3a,4,8,9a-tetrahydro-3H-furo[3,2-g]isochromene-2,9-dione |
