Introduction：Basic information about CAS 104518-25-4|m-PEG7-Br, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | m-PEG7-Br |
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| CAS Number | 104518-25-4 | Molecular Weight | 403.30600 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C15H31BrO7 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | methoxy hepta(ethylene glycol)bromide |
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| Synonym | More Synonyms |
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m-PEG7-Br BiologicalActivity
| Description | m-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. |
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Chemical & Physical Properties
| Molecular Formula | C15H31BrO7 |
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| Molecular Weight | 403.30600 |
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| Exact Mass | 402.12500 |
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| PSA | 64.61000 |
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| LogP | 1.12730 |
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Safety Information
Synonyms
| 1-{2-[2-(2-Bromo-ethoxy)-ethoxy]-ethoxy}-2-{2-[2-(2-methoxy-ethoxy)-ethoxy]-ethoxy}-ethane |
| m-PEG-7-Br |
| mPEG7-Br |
| m-PEG-7-bromide |
