CAS 81348-83-6|Momordicoside L

Introduction:Basic information about CAS 81348-83-6|Momordicoside L, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameMomordicoside L
CAS Number81348-83-6Molecular Weight634.84000
Density1.24±0.1 g/cm3Boiling Point756.9±60.0 °C at 760 mmHg
Molecular FormulaC36H58O9Melting Point/
MSDS/Flash Point/

Names

Name(3β,7β,9β,10α,17β)-7-(β-D-glucopyranosyloxy)-3-hydroxy-17-[(3E)-5-hydroxy-1,5-dimethylhex-3-en-1-yl]-4,4,14-trimethylestr-5-ene-9-carboxaldehyde
SynonymMore Synonyms

Momordicoside L BiologicalActivity

DescriptionMomordicoside L is a Cucurbitane Triterpenoid, that can be isolated from the leaves of Momordica charantia. Momordicoside L shows anticancer activity[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>Others >>Others
In VitroMomordicoside L 对 HL60(白血病)、CRL1579(黑色素瘤)、A549(肺)、SK-BR-3(乳腺)和 AZ521(胃)细胞显示出中度细胞毒性,IC50 值分别为 37.2 ± 2.7、11.9 ± 2.2、>50、>50 和 19.9 ± 1.5 μM[1]。
References

[1]. Zhang J, et al. Cucurbitane triterpenoids from the leaves of Momordica charantia, and their cancer chemopreventive effects and cytotoxicities. Chem Biodivers. 2012 Feb;9(2):428-40.  

Chemical & Physical Properties

Density1.24±0.1 g/cm3
Boiling Point756.9±60.0 °C at 760 mmHg
Molecular FormulaC36H58O9
Molecular Weight634.84000
Exact Mass634.40800
PSA156.91000
LogP3.27980

Synonyms

3-hydroxy-17-(5-hydroxy-1,5-dimethyl-hex-3-enyl)-4,4,13,14-tetramethyl-7-(3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-1,2,3,4,7,8,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthrene-9-carbaldehyde
3β,25-dihydroxy-19-oxo-cucurbita-5,23-diene-7β-yl β-D-glucopyranoside
momordicoside K
momordicoside L
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