CAS 5088-90-4|Liensinine diperchlorate

Introduction：Basic information about CAS 5088-90-4|Liensinine diperchlorate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Liensinine diperchlorate BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	Liensinine diperchlorate
CAS Number	5088-90-4	Molecular Weight	711.198
Density	/	Boiling Point	/
Molecular Formula	C₃₇H₄₄Cl₂N₂O₁₄	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	4-[(6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl)methyl]-2-{[(1R)-1-(4-hydroxybenzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydro-7-isoquinolinyl]oxy}phenol perchlorate (1:1)
Synonym	More Synonyms

Liensinine diperchlorate BiologicalActivity

Description	Liensinine Diperchlorate is a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn. Liensinine Diperchlorate inhibits late-stage autophagy/mitophagy through blocking autophagosome-lysosome fusion. Liensinine Diperchlorate has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc[1].
Related Catalog	Signaling Pathways >>Autophagy >>AutophagySignaling Pathways >>Autophagy >>Mitophagy
References	[1]. Zhou J, et al. A novel autophagy/mitophagy inhibitor liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fission. Autophagy. 2015;11(8):1259-79.

Chemical & Physical Properties

Molecular Formula	C₃₇H₄₄Cl₂N₂O₁₄
Molecular Weight	711.198
Exact Mass	710.260620
InChIKey	BGUPXKYVHOSZPY-UHFFFAOYSA-N
SMILES	COc1cc2c(cc1OC)C(Cc1ccc(O)c(Oc3cc4c(cc3OC)CCN(C)C4Cc3ccc(O)cc3)c1)N(C)CC2.[O-][Cl+3]([O-])([O-])O.[O-][Cl+3]([O-])([O-])O

Safety Information

HS Code	29389090

Synonyms

Phenol, 4-[(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl]-2-[[(1R)-1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-7-isoquinolinyl]oxy]-, perchlorate (1:1) (salt)

4-[(6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl)methyl]-2-{[(1R)-1-(4-hydroxybenzyl)-6-methoxy-2-methyl-1,2,3,4-tetrahydro-7-isoquinolinyl]oxy}phenol perchlorate (1:1)

Liensinine diperchlorate

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