Introduction:Basic information about CAS 60842-46-8|FITC Dextran, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | FITC Dextran |
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| CAS Number | 60842-46-8 | Molecular Weight | / |
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Names
| Name | FLUORESCEIN ISOTHIOCYANATE-DEXTRAN |
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| Synonym | More Synonyms |
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FITC Dextran BiologicalActivity
| Description | FITC-Dextran is a marker consisting of coupling fluorescein-isothiocyanate to dextran. FITC-Dextrans are polysaccharides comprised of varying lengths of branched glucose molecules which available in molecular weights ranging from 4-70 kDa and can be used to determine solute, ion and protein permeability of the blood-brain barrier (BBB) based on the size of the dextran used[1][2][3]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Natarajan R, et al. Fluorescein Isothiocyanate (FITC)-Dextran Extravasation as a Measure of Blood-Brain Barrier Permeability. Curr Protoc Neurosci. 2017 Apr 10;79:9.58.1-9.58.15. [2]. Hoffmann A, et al. High and Low Molecular Weight Fluorescein Isothiocyanate (FITC)-Dextrans to Assess Blood-Brain Barrier Disruption: Technical Considerations. Transl Stroke Res. 2011 Mar;2(1):106-11. [3]. Eriksson I, et al. Analysis of Lysosomal pH by Flow Cytometry Using FITC-Dextran Loaded Cells. Methods Mol Biol. 2017;1594:179-189. |
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Chemical & Physical Properties
Safety Information
Synonyms