CAS 11028-71-0|Concanavalin A
| Common Name | Concanavalin A | ||
|---|---|---|---|
| CAS Number | 11028-71-0 | Molecular Weight | 304.35 |
| Density | / | Boiling Point | / |
| Molecular Formula | C15H24 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 39 °C |
| Symbol | GHS08 | Signal Word | Danger |
Names
| Name | Concanavalin A |
|---|---|
| Synonym | More Synonyms |
Concanavalin A BiologicalActivity
| Description | Concanavalin A is a Ca2+/Mn2+-dependent and mannose/glucose-binding plant lectin that can be found in jack bean. Concanavalin A can induce programmed cell death[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Apoptosis >>ApoptosisResearch Areas >>CancerResearch Areas >>InfectionResearch Areas >>Inflammation/Immunology |
| References | [1]. Li W, et, al. Concanavalin A: a potential anti-neoplastic agent targeting apoptosis, autophagy and anti-angiogenesis for cancer therapeutics. Biochem Biophys Res Commun. 2011 Oct 22;414(2):282-6. [2]. Cantelli A, et, al. Concanavalin A-Rose Bengal bioconjugate for targeted Gram-negative antimicrobial photodynamic therapy. J Photochem Photobiol B. 2020 Mar 13;206:111852. |
Chemical & Physical Properties
| Molecular Formula | C15H24 |
|---|---|
| Molecular Weight | 304.35 |
| Flash Point | 39 °C |
| Appearance of Characters | powder |
| Storage condition | 2-8°C |
| Water Solubility | PBS: 5 mg/mL, slightly hazy | Slightly soluble in water and phosfate buffered saline. |
Safety Information
| Symbol | GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H317-H334-H361 |
| Precautionary Statements | P261-P280-P284-P304 + P340-P342 + P311 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn |
| Risk Phrases | R42/43 |
| Safety Phrases | S36;S24/25 |
| RIDADR | UN 1170 3/PG 3 |
| WGK Germany | 3 |
| RTECS | GK6890000 |
| HS Code | 35040090 |
Articles83
More Articles| The second virial coefficient as a predictor of protein aggregation propensity: A self-interaction chromatography study. Eur. J. Pharm. Biopharm. 96 , 282-90, (2015) The second osmotic virial coefficients (b2) of four proteins - lysozyme, recombinant human lactoferrin, concanavalin A and catalase were measured by self-interaction chromatography (SIC) in solutions ... | |
| Osmolyte effects on the self-association of concanavalin A: testing theoretical models. Biochemistry 52(51) , 9367-74, (2013) The formation and stability of protein-protein interfaces are of obvious biological importance. While a large body of literature exists describing the effect of osmolytes on protein folding, very few ... | |
| Cellular interaction of nontypeable Haemophilus influenzae triggers cytotoxicity of infected type II alveolar cells via apoptosis. Pathog. Dis. 73(2) , 1-12, (2015) Nontypeable Haemophilus influenzae (NTHi) is an important cause of lower respiratory tract infections, resulting in exacerbations of chronic obstructive pulmonary disease (COPD). Despite its pathogeni... |
Synonyms
| EINECS 234-258-2 |
| MFCD00071069 |
