CAS 9027-67-2|Terminal Deoxynucleotidyl Transferase
| Common Name | Terminal Deoxynucleotidyl Transferase | ||
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| CAS Number | 9027-67-2 | Molecular Weight | / |
| Density | / | Boiling Point | / |
| Molecular Formula | / | Melting Point | / |
| MSDS | USA | Flash Point | / |
Names
| Name | Terminal Deoxynucleotidyl Transferase |
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| Synonym | More Synonyms |
Terminal Deoxynucleotidyl Transferase BiologicalActivity
| Description | Terminal deoxyribonucleotidyltransferase (TdT) catalyses the condensation of deoxyribonucleotide triphosphates onto the 3' hydroxyl ends of DNA strands and adds N-regions to gene segment junctions during V(D)J recombination. Terminal deoxyribonucleotidyltransferase is expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia/lymphoma cells[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Boulé JB, et, al. Terminal deoxynucleotidyl transferase indiscriminately incorporates ribonucleotides and deoxyribonucleotides. J Biol Chem. 2001 Aug 17;276(33):31388-93. |
Chemical & Physical Properties
| No Any Chemical & Physical Properties |
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US) |
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| RIDADR | NONH for all modes of transport |
Articles45
More Articles| TdT+ T-lymphoblastic populations are increased in Castleman disease, in Castleman disease in association with follicular dendritic cell tumors, and in angioimmunoblastic T-cell lymphoma. Am. J. Surg. Pathol. 36(11) , 1619-28, (2012) T-lymphoblastic lymphoma is an aggressive neoplasm requiring prompt clinical treatment. Conversely, indolent T-lymphoblastic proliferation mimics T-lymphoblastic lymphoma but consists of a proliferati... | |
| The pattern of gene expression and gene dose profiles of 6-Mercaptopurine- and 6-Thioguanine-resistant human leukemia cells. Biochem. Biophys. Res. Commun. 411(1) , 156-61, (2011) Exposure of MOLT4 human T-cell leukemia cells to 6-Mercaptopurine (6-MP) and 6-Thioguanine (6-TG) resulted in acquired resistance associated with attenuated expression of the genes encoding concentrat... | |
| Polymerase incorporation of pyrene-nucleoside triphosphates. Bioorg. Med. Chem. Lett. 22(13) , 4428-30, (2012) Pyrene-deoxynucleoside triphosphates (dPTPs), varying by the positioning of the aromatic system, were synthesized. Their ability to function as substrates for the Klenow fragment of Escherichia coli D... |
Synonyms
| MFCD00166324 |
