Introduction：Basic information about CAS 144089-97-4|DMT-2'Fluoro-DG(IB) Amidite, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | DMT-2'Fluoro-DG(IB) Amidite |
|---|
| CAS Number | 144089-97-4 | Molecular Weight | 857.906 |
|---|
| Density | / | Boiling Point | / |
|---|
| Molecular Formula | C44H53FN7O8P | Melting Point | / |
|---|
| MSDS | / | Flash Point | / |
|---|
Names
| Name | 2'-F-ibu-dG Phosphoramidite |
|---|
| Synonym | More Synonyms |
|---|
DMT-2'Fluoro-DG(IB) Amidite BiologicalActivity
| Description | DMT-2'Fluoro-DG(IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a nucleoside that can be used in the preparation of 4'-modified 2'-deoxy-2'-fluorouridine[1]. |
|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
|---|
| References | [1]. Elise Malek-Adamian, et al. 4'-C-Methoxy-2'-deoxy-2'-fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing. J Am Chem Soc. 2017 Oct 18;139(41):14542-14555. |
|---|
Chemical & Physical Properties
| Molecular Formula | C44H53FN7O8P |
|---|
| Molecular Weight | 857.906 |
|---|
| Exact Mass | 857.367737 |
|---|
| LogP | 9.87 |
|---|
| InChIKey | KJFUMXZZVYMQEU-AOCJBPQJSA-N |
|---|
| SMILES | COc1ccc(C(OCC2OC(n3cnc4c(=O)[nH]c(NC(=O)C(C)C)nc43)C(F)C2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1 |
|---|
Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|
| RIDADR | NONH for all modes of transport |
|---|
Synonyms
| 9-{(3ξ)-5-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-2-fluoro-β-D-threo-pentofuranosyl}-2-(isobutyrylamino)-1,9-dihydro-6H-purin-6-one |
| 6H-Purin-6-one, 9-[(3ξ)-5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-threo-pentofuranosyl]-1,9-dihydro-2-[(2-methyl-1-oxoprop yl)amino]- |
