CAS 761425-93-8|Clematichinenoside AR

Introduction:Basic information about CAS 761425-93-8|Clematichinenoside AR, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameClematichinenoside AR
CAS Number761425-93-8Molecular Weight1807.93
Density1.58±0.1 g/cm3Boiling Point/
Molecular FormulaC82H134O43Melting Point/
MSDS/Flash Point/

Names

NameClematichinenoside AR

Clematichinenoside AR BiologicalActivity

DescriptionClematichinenoside AR is a major active ingredient that could be extracted from the traditional Chinese herb Clematis chinensis and has potent pharmacological effects on various diseases, including atherosclerosis (AS)[1].
Related CatalogSignaling Pathways >>Autophagy >>AutophagyResearch Areas >>Inflammation/Immunology
In VitroClematichinenoside AR alleviates foam cell formation and the inflammatory response in Ox-LDL-induced RAW264.7 cells by activating autophagy[1].
In VivoClematichinenoside AR induces immunosuppression involving Treg cells in Peyer's patches of rats with adjuvant induced arthritis[2].
References

[1]. Yajing Diao, et al. Clematichinenoside AR Alleviates Foam Cell Formation and the Inflammatory Response in Ox-LDL-Induced RAW264.7 Cells by Activating Autophagy. Inflammation. 2021 Apr;44(2):758-768.

[2]. Ying Xiong, et al. Clematichinenoside AR induces immunosuppression involving Treg cells in Peyer׳s patches of rats with adjuvant induced arthritis. J Ethnopharmacol. 2014 Sep 11;155(2):1306-14.

Chemical & Physical Properties

Density1.58±0.1 g/cm3
Molecular FormulaC82H134O43
Molecular Weight1807.93
InChIKeyJFLCHMJGYAFQIU-AOXNNHMFSA-N
SMILESCC1OC(OCC2OC(OC3C(CO)OC(OC4COC(OC5C(O)C(C)OC(OC6C(OC7CCC8(C)C(CCC9(C)C8CC=C8C%10CC(C)(C)CCC%10(C(=O)OC%10OC(COC%11OC(CO)C(OC%12OC(C)C(O)C(O)C%12O)C(O)C%11O)C(O)C(O)C%10O)CCC89C)C7(C)C)OCC(O)C6O)C5O)C(O)C4O)C(O)C3O)C(O)C(O)C2O)C(O)C(O)C1O

Safety Information

Hazard CodesXi
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