Introduction：Basic information about CAS 460738-38-9|Ecallantide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Ecallantide |
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| CAS Number | 460738-38-9 | Molecular Weight | / |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C305H441N88O91S8 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | ecallantide |
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| Synonym | More Synonyms |
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Ecallantide BiologicalActivity
| Description | Ecallantide (DX-88) is a specific recombinant plasma kallikrein inhibitor. Ecallantide inhibits the production of bradykinin. Ecallantide can be used to prevent acute attacks of angioedema[1]. |
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| Related Catalog | Signaling Pathways >>Metabolic Enzyme/Protease >>Ser/Thr ProteaseResearch Areas >>Cardiovascular Disease |
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| References | [1]. Martello JL, et al. Ecallantide for treatment of acute attacks of hereditary angioedema. Am J Health Syst Pharm. 2012 Apr 15;69(8):651-7. |
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Chemical & Physical Properties
| Molecular Formula | C305H441N88O91S8 |
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| InChIKey | VBGWSQKGUZHFPS-BRUBJIIKSA-N |
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| SMILES | CCC(C)C1NC(=O)C(Cc2ccccc2)NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C2CSSCC3NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CCC(=O)O)NC(=O)C(Cc4ccccc4)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)CNC(=O)C(CCC(=O)O)NC(=O)C(CSSCC(NC(=O)C4CCCN4C(=O)CNC(=O)C(CC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C(CCCCN)NC(=O)C(Cc4ccccc4)NC(=O)C(C)NC(=O)C(NC(=O)C(Cc4ccccc4)NC(=O)C(CO)NC(=O)C(Cc4cnc[nH]4)NC(=O)C(CCSC)NC(=O)C(C)NC(=O)C(N)CCC(=O)O)CSSCC(C(=O)NC(C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)O)C(=O)O)C(C)O)NC(=O)C(CCSC)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC3=O)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(C)C(=O)NC(Cc3cnc[nH]3)C(=O)N3CCCC3C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc3c[nH]c4ccccc34)C(=O)NC(Cc3ccccc3)C(=O)NC(Cc3ccccc3)C(=O)NC(CC(N)=O)C(=O)NC(C(C)CC)C(=O)NC(Cc3ccccc3)C(=O)NC(C(C)O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(N)=O)C(=O)N2)NC(=O)CNC(=O)CNC(=O)C(Cc2ccc(O)cc2)NC1=O |
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Synonyms
