CAS 890056-27-6|Custirsen

Introduction：Basic information about CAS 890056-27-6|Custirsen, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameCustirsen
CAS Number890056-27-6Molecular Weight/
Density/Boiling Point/
Molecular FormulaC231H312N78O119P20S20Melting Point/
MSDS/Flash Point/

Names

NameCustirsen
SynonymMore Synonyms

Custirsen BiologicalActivity

DescriptionCustirsen is a highly specific antisense oligonucleotide that inhibits the production of clusterin , an antiapoptotic protein that is upregulated in response to chemotherapy and that confers treatment resistance.
Related CatalogResearch Areas >>CancerSignaling Pathways >>Others >>Others
References

[1]. Chi KN, Eisenhauer E, Fazli L, et al. A phase I pharmacokinetic and pharmacodynamic study of OGX-011, a 2'-methoxyethyl antisense oligonucleotide to clusterin, in patients with localized prostate cancer. J Natl Cancer Inst. 2005;97(17):1287-1296.

Chemical & Physical Properties

Molecular FormulaC231H312N78O119P20S20
InChIKeyRCFZILUHCNXXFY-UHFFFAOYSA-N
SMILESCOCCOC1C(O)C(COP(O)(=S)OC2C(COP(O)(=S)OC3C(COP(O)(=S)OC4C(COP(O)(=S)OC5CC(n6cnc7c(N)ncnc76)OC5COP(O)(=S)OC5CC(n6ccc(N)nc6=O)OC5COP(O)(=S)OC5CC(n6cc(C)c(=O)[nH]c6=O)OC5COP(O)(=S)OC5CC(n6cc(C)c(=O)[nH]c6=O)OC5COP(O)(=S)OC5CC(n6ccc(N)nc6=O)OC5COP(O)(=S)OC5CC(n6cc(C)c(=O)[nH]c6=O)OC5COP(O)(=S)OC5CC(n6cnc7c(=O)[nH]c(N)nc76)OC5COP(O)(=S)OC5CC(n6cnc7c(N)ncnc76)OC5COP(O)(=S)OC5CC(n6cnc7c(=O)[nH]c(N)nc76)OC5COP(O)(=S)OC5CC(n6cnc7c(N)ncnc76)OC5COP(O)(=S)OC5CC(n6ccc(N)nc6=O)OC5COP(O)(=S)OC5CC(n6cnc7c(=O)[nH]c(N)nc76)OC5COP(O)(=S)OC5CC(n6cnc7c(N)ncnc76)OC5COP(O)(=S)OC5C(COP(O)(=S)OC6C(COP(O)(=S)OC7C(COP(O)(=S)OC8C(CO)OC(n9cc(C)c(N)nc9=O)C8OCCOC)OC(n8cnc9c(N)ncnc98)C7OCCOC)OC(n7cnc8c(=O)[nH]c(N)nc87)C6OCCOC)OC(n6cc(C)c(N)nc6=O)C5OCCOC)OC(n5cc(C)c(=O)[nH]c5=O)C4OCCOC)OC(n4cc(C)c(N)nc4=O)C3OCCOC)OC(n3cnc4c(N)ncnc43)C2OCCOC)OC1n1cc(C)c(=O)[nH]c1=O

Synonyms

Custirsen
CAS 81286-16-0|Somatostatin-28 (1-12)
CAS 936694-12-1|Glesatinib
Recommended......
CAS 89-72-5|2-sec-Butylphenol CAS 89167-34-0|4-Chloro-3-iodo CAS 89694-46-2|(2-Chloro-5-met CAS 894-71-3|Nortriptyline Hyd CAS 89536-84-5|Boc-N-methyl-D- CAS 89536-85-6|Boc-DN-Me-Val-O CAS 898747-12-1|4-Methoxy-1H-i CAS 893566-31-9|3-Methoxy-4-me CAS 89028-37-5|BIS(1-BENZOTRIA CAS 893637-97-3|4'-CHLORO- CAS 89205-07-2|5-(4-methoxyphe CAS 898787-03-6|2,5-dimethoxyb CAS 89268-03-1|1-[(Chlorometho CAS 899822-97-0|3-Nitro-1-(4-o CAS 89007-51-2|2,6-dichloropip CAS 89464-26-6|TETRAHYDRO-2H-P CAS 89483-07-8|Boc-L-Cycloprop CAS 893745-85-2|4-(1-PIPERIDIN CAS 89001-53-6|p-Nitro-α CAS 89073-57-4|1,3-DIPROPYL-8-
Disclaimer

This site is a non-commercial website, not accept any sponsorship and advertising. The content is collated from the Internet, does not represent the position of this site, for personal reference only, please distinguish by yourself! The belongs to the original author.

Copyright © 2025 All Rights Reserved.

TOP